Mesoporous silica nanoparticles for pulmonary drug delivery

A Garcia-Fernandez, F Sancenon… - Advanced Drug Delivery …, 2021 - Elsevier
Over the last years, respiratory diseases represent a clinical concern, being included among
the leading causes of death in the world due to the lack of effective lung therapies, mainly …

Single-micelle-directed synthesis of mesoporous materials

T Zhao, A Elzatahry, X Li, D Zhao - Nature Reviews Materials, 2019 - nature.com
Functional mesoporous materials with multilevel architectures, ranging from 0D to 3D, are
typically prepared using surfactant-templating methods. In these methods, surfactants first …

Ultrafast directional Janus Pt–mesoporous silica nanomotors for smart drug delivery

P Díez, E Lucena-Sánchez, A Escudero… - ACS …, 2021 - ACS Publications
Development of bioinspired nanomachines with an efficient propulsion and cargo-towing
has attracted much attention in the last years due to their potential biosensing, diagnostics …

The pathway to intelligence: using stimuli‐responsive materials as building blocks for constructing smart and functional systems

X Zhang, L Chen, KH Lim, S Gonuguntla… - Advanced …, 2019 - Wiley Online Library
Abstract Systems that are intelligent have the ability to sense their surroundings, analyze,
and respond accordingly. In nature, many biological systems are considered intelligent (eg …

Enzyme-powered gated mesoporous silica nanomotors for on-command intracellular payload delivery

A Llopis-Lorente, A Garcia-Fernandez… - ACS …, 2019 - ACS Publications
The introduction of stimuli-responsive cargo release capabilities on self-propelled micro-and
nanomotors holds enormous potential in a number of applications in the biomedical field …

Mesoporous silica‐based materials with bactericidal properties

A Bernardos, E Piacenza, F Sancenon, M Hamidi… - Small, 2019 - Wiley Online Library
Bacterial infections are the main cause of chronic infections and even mortality. In fact, due
to extensive use of antibiotics and, then, emergence of antibiotic resistance, treatment of …

Intercellular communication between artificial cells by allosteric amplification of a molecular signal

BC Buddingh', J Elzinga, JCM van Hest - Nature communications, 2020 - nature.com
Multicellular organisms rely on intercellular communication to coordinate the behaviour of
individual cells, which enables their differentiation and hierarchical organization. Various …

Advanced smart nanomaterials with integrated logic-gating and biocomputing: dawn of theranostic nanorobots

AA Tregubov, PI Nikitin, MP Nikitin - Chemical reviews, 2018 - ACS Publications
Accurate and precise drug delivery is the key to successful therapy. Monoclonal antibodies,
which can transport therapeutic payload to cells expressing specific markers, have paved …

New advances in in vivo applications of gated mesoporous silica as drug delivery nanocarriers

A García‐Fernández, E Aznar, R Martínez‐Máñez… - Small, 2020 - Wiley Online Library
One appealing concept in the field of hybrid materials is related to the design of gated
materials. These materials are prepared in such a way that the release of chemical or …

Delivery of miR-200c-3p using tumor-targeted mesoporous silica nanoparticles for breast cancer therapy

I Garrido-Cano, A Adam-Artigues… - … Applied Materials & …, 2023 - ACS Publications
Despite advances in breast cancer treatment, it remains the leading cause of cancer-related
death in women worldwide. In this context, microRNAs have emerged as potential …