This article reviews findings up to the end of 1997 about the inducible transcription factors
(ITFs) c-Jun, JunB, JunD, c-Fos, FosB, Fra-1, Fra-2, Krox-20 (Egr-2) and Krox-24 (NGFI-A …

Apoptosis is now recognized as a normal feature in the development of the nervous system
and may also play a role in neurodegenerative diseases and aging. This phenomenon has …

A CNS catecholaminergic cell line, Cath. a, was established by targeted oncogenesis in
transgenic mice. Cath. a cells express neuronal properties but lack neuronal morphology …

The dependence of some cell types on serum factors for growth may represent a powerful,
but poorly studied, model for antimitogenic pathways. In this study, we examine ceramide as …

Using immunohistochemistry we have analysed the nuclear expression of cyclins A, B, D,
and E in neurones in the hippocampi of control subjects and patients suffering from various …

In this review, we consider apoptosis as a process intimately linked to the cell cycle. There
are several reasons for thinking of apoptosis as a cell cycle phenomenon. First, within the …

Perinatal exposure to infectious agents and toxins is linked to the pathogenesis of
neuropsychiatric disorders, but the mechanisms by which environmental triggers interact …

The mechanism of cell death in the brains of patients with acquired immune deficiency
syndrome was examined in 15 cases, 8 of whom had human immunodeficiency virus (HIV) …

Overexpression of the gene encoding the 70-kDa heat shock protein (hsp70) has previously
been shown to protect neuronal cells against subsequent thermal or ischemic stress. It has …

Cerebrolysin (EBEWE Arzneimittel, Austria, Europe) is a widely used drug relieving the
symptoms of a variety of neurological disorders, particularly of neurodegenerative dementia …