The Hippo pathway is an evolutionarily conserved signalling pathway with key roles in
organ development, epithelial homeostasis, tissue regeneration, wound healing and …

Synapses, the fundamental unit in neuronal circuits, are critical for learning and memory,
perception, thinking, and reaction. The neuromuscular junction (NMJ) is a synapse formed …

YAP (yes-associated protein) is a transcriptional factor that is negatively regulated by Hippo
pathway, a conserved pathway for the development and size control of multiple organs. The …

The neuromuscular junction (NMJ) is a specialized synapse that bridges the motor neuron
and the skeletal muscle fiber and is crucial for conversion of electrical impulses originating …

During embryogenesis, the musculoskeletal system develops while containing within itself a
force generator in the form of the musculature. This generator becomes functional relatively …

Autism spectrum disorders (ASD) are a group of neurodevelopmental disorders with
symptoms including social deficits, anxiety, and communication difficulties. However, ASD …

Yes‑associated protein (YAP) acts as a transcriptional co‑activator in gene expression and
cell proliferation control by binding to the transcriptional factor TEA domain (TEAD) of the …

Hippo signaling pathway is a highly conserved and familiar tissue growth regulator, primarily
dealing with cell survival, cell proliferation, and apoptosis. The Yes‐associated protein …

• The maintenance of skeletal muscle mass is controlled by a complex signaling network that
functions in concert to maintain homeostasis.• The Hippo signaling pathway controls skeletal …

Abstract We examined YAP1/TAZ-TEAD signaling pathway activity at neuromuscular
junctions (NMJs) of skeletal muscle fibers in adult mice. Our investigations revealed that …