C-type lectin-like receptors as emerging orchestrators of sterile inflammation represent potential therapeutic targets

E Chiffoleau - Frontiers in immunology, 2018 - frontiersin.org
Over the last decade, C-type lectin-like receptors (CTLRs), expressed mostly by myeloid
cells, have gained increasing attention for their role in the fine tuning of both innate and …

Cancer stem cell markers in head and neck squamous cell carcinoma

AG Major, LP Pitty, CS Farah - Stem cells international, 2013 - Wiley Online Library
Head and neck squamous cell carcinoma (HNSCC) is one of the world's top ten most
common cancers. Current survival rates are poor with only 50% of patients expected to …

[HTML][HTML] Diffuse malignant peritoneal mesothelioma: long-term survival with complete cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy …

D Baratti, S Kusamura, AD Cabras, R Bertulli… - European Journal of …, 2013 - Elsevier
Background Prognosis of diffuse malignant peritoneal mesothelioma (DMPM) has been
recently improved by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy …

Platelet CLEC-2 and podoplanin in cancer metastasis

KL Lowe, L Navarro-Nunez, SP Watson - Thrombosis research, 2012 - Elsevier
It has long been recognised that the function of platelets in health and disease span far
beyond their roles in haemostasis and thrombosis. The observation that tumour cells induce …

Podoplanin expression by cancer‐associated fibroblasts predicts poor outcome in invasive ductal breast carcinoma

B Pula, A Jethon, A Piotrowska, A Gomulkiewicz… - …, 2011 - Wiley Online Library
Pula B, Jethon A, Piotrowska A, Gomulkiewicz A, Owczarek T, Calik J, Wojnar A, Witkiewicz
W, Rys J, Ugorski M, Dziegiel P & Podhorska‐Okolow M (2011) Histopathology 59, 1249 …

Podoplanin expression in oral leukoplakia: tumorigenic role

JC de Vicente, JP Rodrigo, T Rodriguez-Santamarta… - Oral oncology, 2013 - Elsevier
OBJECTIVES: Recent studies have identified podoplanin, a mucin-type transmembrane
glycoprotein, as a biomarker for oral cancer risk in patients with oral leukoplakia (OPL). The …

New insights into the role of podoplanin in epithelial–mesenchymal transition

J Renart, P Carrasco-Ramírez… - International review of …, 2015 - Elsevier
Podoplanin is a small mucin-like transmembrane protein expressed in several adult tissues
and with an important role during embryogenesis. It is needed for the proper development of …

Pathway-related molecules of VEGFC/D-VEGFR3/NRP2 axis in tumor lymphangiogenesis and lymphatic metastasis

J Wang, Y Huang, J Zhang, Y Wei, S Mahoud… - Clinica Chimica …, 2016 - Elsevier
Precondition for tumor lymphatic metastasis is that tumor cells induce formation of original
and newborn lymphatic vessels and invade surrounding lymphatic vessels in tumor stroma …

Podoplanin expression correlates with sentinel lymph node metastasis in early squamous cell carcinomas of the oral cavity and oropharynx

GF Huber, FR Fritzsche, L Züllig, M Storz… - … journal of cancer, 2011 - Wiley Online Library
In patients with early head and neck squamous cell carcinoma (HNSCC), occult lymph node
metastasis is difficult to predict by clinical or pathological parameters. However, such …

The emerging role of NANOG as an early cancer risk biomarker in patients with oral potentially malignant disorders

JC de Vicente, T Rodríguez-Santamarta… - Journal of clinical …, 2019 - mdpi.com
NANOG, a key regulator of pluripotency and self-renewal in embryonic and adult stem cells,
is frequently overexpressed in multiple cancers, including oral squamous cell carcinoma …