Thiamine or vitamin B1 is an essential, water-soluble vitamin required for mitochondrial
energetics—the production of adenosine triphosphate (ATP). It is a critical and rate-limiting …

Abstract Background Approximately 5.7 million Americans carry the diagnosis of systolic
heart failure (HF), a major health care burden. HF is a known manifestation of thiamine …

Thiamin (vitamin B1) is a cofactor required for essential biochemical reactions in all living
organisms, yet free thiamin is scarce in the environment. The diversity of biochemical …

Thiamine supplementation may prevent and reverse early‐stage diabetic nephropathy. This
probably occurs by correcting diabetes‐linked increased clearance of thiamine, maintaining …

Little information is available to estimate water-soluble vitamin intakes from urinary vitamins
and their metabolite contents as possible nutritional markers. Determination of the …

Increased renal clearance of thiamine (vitamin B1) occurs in experimental and clinical
diabetes producing thiamine insufficiency mediated by impaired tubular re-uptake and …

The number of people living with chronic kidney disease (CKD) is growing as our global
population continues to expand. With aging, diabetes, and cardiovascular disease being …

BACKGROUND: Diabetes is associated with mishandling of thiamine in the kidney and
development of diabetic nephropathy. The aim of this study is to assess the disturbance of …

Following a request from the European Commission, the EFSA Panel on Dietetic Products,
Nutrition and Allergies (NDA) derived dietary reference values (DRV s) for thiamin (vitamin …

Recent pet food recalls for insufficient dietary thiamine have highlighted the importance of
adequate thiamine intake in dogs and cats, as thiamine is an essential dietary nutrient with a …