Mechanisms for DNA charge transport

JC Genereux, JK Barton - Chemical reviews, 2010 - ACS Publications
DNA charge transport (CT) chemistry has received considerable attention by scientific
researchers over the past 15 years since our first provocative publication on long-range CT …

One-electron oxidation reactions of purine and pyrimidine bases in cellular DNA

J Cadet, JR Wagner, V Shafirovich… - International journal of …, 2014 - Taylor & Francis
Purpose: The aim of this survey is to critically review the available information on one-
electron oxidation reactions of nucleobases in cellular DNA with emphasis on damage …

Translocation and deletion breakpoints in cancer genomes are associated with potential non-B DNA-forming sequences

A Bacolla, JA Tainer, KM Vasquez… - Nucleic acids …, 2016 - academic.oup.com
Gross chromosomal rearrangements (including translocations, deletions, insertions and
duplications) are a hallmark of cancer genomes and often create oncogenic fusion genes …

Proton-coupled electron transfer in DNA on formation of radiation-produced ion radicals

A Kumar, MD Sevilla - Chemical reviews, 2010 - ACS Publications
It is well established that exposure of DNA to high-energy radiation results in a variety of
physical and chemical changes in DNA including strand breakage, mutation, and DNA …

G-quadruplex folds of the human telomere sequence alter the site reactivity and reaction pathway of guanine oxidation compared to duplex DNA

AM Fleming, CJ Burrows - Chemical research in toxicology, 2013 - ACS Publications
Telomere shortening occurs during oxidative and inflammatory stress with guanine (G) as
the major site of damage. In this work, a comprehensive profile of the sites of oxidation and …

Reaction of electrons with DNA: radiation damage to radiosensitization

A Kumar, D Becker, A Adhikary, MD Sevilla - International Journal of …, 2019 - mdpi.com
This review article provides a concise overview of electron involvement in DNA radiation
damage. The review begins with the various states of radiation-produced electrons …

Charged particle and photon interactions with matter: recent advances, applications, and interfaces

Y Hatano, Y Katsumura, A Mozumder - 2010 - books.google.com
Covering state-of-the-art advances, novel applications, and future perspectives, this volume
presents new directions on the basic studies of charged particle and photon interactions with …

Hydroxyl Radical (OH) Reaction with Guanine in an Aqueous Environment: A DFT Study

A Kumar, V Pottiboyina, MD Sevilla - The Journal of Physical …, 2011 - ACS Publications
The reaction of hydroxyl radical (OH•) with DNA accounts for about half of radiation-induced
DNA damage in living systems. Previous literature reports point out that the reaction of OH• …

Mechanistic aspects of hydration of guanine radical cations in DNA

Y Rokhlenko, J Cadet, NE Geacintov… - Journal of the …, 2014 - ACS Publications
The mechanistic aspects of hydration of guanine radical cations, G•+ in double-and single-
stranded oligonucleotides were investigated by direct time-resolved spectroscopic …

Early events in radiobiology: Isolated and cluster DNA damage induced by initial cations and nonionizing secondary electrons

Y Dong, H Liao, Y Gao, P Cloutier… - The Journal of …, 2021 - ACS Publications
Radiobiological damage is principally triggered by an initial cation and a secondary electron
(SE). We address the fundamental questions: What lesions are first produced in DNA by this …