N-Heterocyclic carbenes are now commonly encountered in organometallic and inorganic
coordination chemistry. The increasing attention they enjoy is due to their ability to act as …

Covering: 2002 to August 2017. This review highlights recent RCM reactions towards the
synthesis of sterically congested natural products. It offers an insight into various synthetic …

The enantioselective total synthesis of (+)‐ophiobolin A is described. This total synthesis
features the construction of the spiro CD ring of (+)‐ophiobolin A through a stereoselective …

Highlighting the impressive potential of tandem and stepwise metathesis/non-metathesis
reactions in synthesis, the present review extends the scope of the newly gained renown of …

Introducing a silyl group at one of the internal olefin positions in diolefinic substrates results
in E-selective olefin formation in macrocyclic ring-forming metathesis. The application of this …

Over the past decade, ruthenium-mediated metathesis transformations, including cross-
metathesis, ring-closing metathesis, enyne metathesis, ring-opening metathesis …

Using click chemistry to enable both structural diversity and proteome profiling within a
natural product derived library, two out of nineteen lipstatin analogues showed similar …

BioA catalyzes the second step of biotin biosynthesis, and this enzyme represents a
potential target to develop new antitubercular agents. Herein we report the design …

We review the most important achievements of the last decade in the field of steroid
synthesis in the presence of palladium catalysts. Various palladium-catalyzed cross …

A modular, 13 step, synthesis of the tetrahydropyran-containing annonaceous acetogenin
pyranicin is reported. Key features are the use of an Achmatowicz oxidation-Kishi reduction …