Plausible therapeutic effects of melatonin and analogs in the dopamine-associated pathophysiology of bipolar disorder

SP Laurence, KCS Pe, J Panmanee… - Journal of Psychiatric …, 2025 - Elsevier
Bipolar disorder (BD) is a significant neuropsychiatric condition characterized by marked
psychological mood disturbances. Despite extensive research on the symptomatology of …

Neurolipidomics in schizophrenia: a not so well-oiled machine

CMZM Del Campo, GL Nicolson, A Sfera - Neuropharmacology, 2024 - Elsevier
Most patients with schizophrenia (SCZ) do not exhibit violent behaviors and are more likely
to be victims rather than perpetrators of violent acts. However, a subgroup of forensic …

MAOA variants and genetic susceptibility to major psychiatric disorders

Z Liu, L Huang, X Luo, L Wu, M Li - Molecular neurobiology, 2016 - Springer
Monoamine oxidase A (MAOA) is a mitochondrial enzyme involved in the metabolism of
several biological amines such as dopamine, norepinephrine, and serotonin, which are …

[HTML][HTML] Genetic Variations of DAOA (rs947267 and rs3918342) and COMT Genes (rs165599 and rs4680) in Schizophrenia and Bipolar I Disorder

L Ahmadi, SRK Nezhad, P Behbahani… - Basic and Clinical …, 2018 - ncbi.nlm.nih.gov
Methods: Blood samples (n= 100 for schizophrenia, n= 100 for bipolar I disorder and n= 127
for case control) were collected from individuals unrelated in the southwest of Iran. The …

[HTML][HTML] The Advent of Nutrigenomics: A Narrative Review with an Emphasis on Psychological Disorders

M Birla, C Choudhary, G Singh, S Gupta… - … Nutrition and Food …, 2022 - ncbi.nlm.nih.gov
A new research field is emerging that combines nutrition and genetics at the molecular level,
namely nutrigenomics. Several aspects of nutrigenomics are examined in this review, with a …

[HTML][HTML] Association analysis of DISC1 gene polymorphisms with Attention-Deficit Hyperactivity Disorder in Iranian population

M Kayyal, A Movafagh, M Hashemi… - Pakistan Journal of …, 2015 - ncbi.nlm.nih.gov
Methods: In this research work, for the first time, we investigated the association of three
SNPs (rs11122330, rs6675281 and rs11122319) in the DISC1 gene with ADHD in Iranian …

The role of macrophage intracellular lipid partitioning in glucose and lipid homeostasis during obesity

K Petkevicius - 2019 - repository.cam.ac.uk
Obesity-associated metabolic disorders are amongst the most prevalent causes of death
worldwide. Understanding how obesity leads to the development of the Metabolic Syndrome …

Genomic basis of psychiatric illnesses and response to psychiatric drug treatment modalities

EE Tsermpini, M Skokou, Z Kordou… - Applied Genomics and …, 2020 - Elsevier
In the past few years, we have witnessed a formidable progress in the field of biological
research of psychiatric diseases, owing much on the revolutionary findings in the field of …

[PDF][PDF] Allelic Diversity of VNTR Polymorphism in Monoamine Oxidase A (MAOA) Gene in Young Women and Men in Mashhad, Iran

SS Hojjati, AA Gaeini, H Rohani… - Journal of Isfahan …, 2020 - jims.mui.ac.ir
Background: Monoamine oxidase A (MAOA) enzyme activity is changed in mood disorders,
as well as lower activity associated with criminal and aggressive behaviors. The MAOA …

Bipolar disorder related functional variants in the calcium channel gene family

NL O'Brien - 2016 - discovery.ucl.ac.uk
Bipolar disorder (BD) is a common highly heritable disorder. The calcium channel gene
family has been widely implicated in BD aetiology and these genes include CACNA1C, and …