Gene transcription is the process by which the genetic codes of organisms are read and
interpreted as a set of instructions for cells to divide, differentiate, migrate, and mature. As …

Activator protein-1 (AP-1) was first identified as a transcriptional factor that binds to an
essential cis-ele-ment of the human metallothionein lla (hMTIla) promoter [1]. AP-1 is …

The unique morphological and excitable properties of nerve cells endow them with
specialized properties that permit the reception, transmission, and storage of information. It …

The proto-oncogene c-fos is expressed in neurons in response to direct stimulation by
growth factors and neurotransmitters. In order to determine whether the c-fos protein (Fos) …

This review concerns how cytoplasmic mRNA half-lives are regulated and how mRNA decay
rates influence gene expression. mRNA stability influences gene expression in virtually all …

The HL-60 cell line, derived from a single patient with acute promyelocytic leukemia,
provides a unique in vitro model system for studying the cellular and molecular events …

Protein kinase C, an enzyme that is activated by the receptor-mediated hydrolysis of inositol
phospholipids, relays information in the form of a variety of extracellular signals across the …

Publisher Summary The fibroblast growth factors (FGFs) constitute a family of closely related
polypeptide mitogens. There are seven members of this family, identified on the basis of …

The promoter regions of several phorbol diester-(TPA-) inducible genes (collagenase,
stromelysin, hMT IIA, and SV40) share a conserved 9 bp motif. Synthetic copies of these …

Binding of the human transcription factor Jun/AP-1 to a conserved 8 bp nucleotide sequence
(TRE) is responsible for increased transcription of different cellular genes in response to …