Although stem cell-based therapy has demonstrated considerable potential to manage
certain diseases more successfully than conventional surgery, it nevertheless comes with …

Circulating Extracellular Vesicles in Human Disease | New England Journal of Medicine Skip to
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Extracellular vesicles (EVs) are a heterogeneous group of natural particles that are relevant
to the treatment of cardiovascular diseases. These endogenous vesicles have certain …

Background: In addition to scalability, human embryonic stem cells (hESCs) have the unique
advantage of allowing their directed differentiation toward lineage-specific cells. Objectives …

Extracellular vesicles (EVs) are recognized as nature's own carriers to transport
macromolecules throughout the body. Hijacking this endogenous communication system …

Membrane vesicles released in the extracellular space are composed of a lipid bilayer
enclosing soluble cytosolic material and nuclear components. Extracellular vesicles include …

Exosomes, as functional paracrine units of therapeutic cells, can partially reproduce the
reparative properties of their parental cells. The constitution of exosomes, as well as their …

The effects of cell therapy on heart regeneration in patients with chronic cardiomyopathy
have been assessed in several clinical trials. These trials can be categorized as those using …

Lipid nanoparticles (LNPs) are currently used to transport functional mRNAs, such as COVID‐
19 mRNA vaccines. The delivery of angiogenic molecules, such as therapeutic VEGF‐A …

Extracellular vesicles (EVs) are well-established mediators of cell-to-cell communication.
EVs can be released by every cell type and they can be classified into three major groups …