Principles of virus uncoating: cues and the snooker ball

Y Yamauchi, UF Greber - Traffic, 2016 - Wiley Online Library
Viruses are spherical or complex shaped carriers of proteins, nucleic acids and sometimes
lipids and sugars. They are metastable and poised for structural changes. These features …

Physical virology: From virus self‐assembly to particle mechanics

P Buzón, S Maity, WH Roos - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
Viruses are highly ordered supramolecular complexes that have evolved to propagate by
hijacking the host cell's machinery. Although viruses are very diverse, spreading through …

Atomic force microscopy analysis of extracellular vesicles

P Parisse, I Rago, L Ulloa Severino… - European biophysics …, 2017 - Springer
Extracellular vesicles (EVs) are small vesicles ensuring transport of molecules between cells
and throughout the body. EVs contain cell type-specific signatures and have been proposed …

Reverse transcription mechanically initiates HIV-1 capsid disassembly

S Rankovic, J Varadarajan, R Ramalho… - Journal of …, 2017 - Am Soc Microbiol
The HIV-1 core consists of the viral genomic RNA and several viral proteins encased within
a conical capsid. After cell entry, the core disassembles in a process termed uncoating …

Structural and mechanical characteristics of exosomes from osteosarcoma cells explored by 3D-atomic force microscopy

A Yurtsever, T Yoshida, AB Behjat, Y Araki… - Nanoscale, 2021 - pubs.rsc.org
Exosomes have recently gained interest as mediators of cell-to-cell communication and as
potential biomarkers for cancer and other diseases. They also have potential as …

Adenovirus core protein V reinforces the capsid and enhances genome release from disrupted particles

N Martín-González, A Gómez-González… - Science …, 2023 - science.org
Out of the three core proteins in human adenovirus, protein V is believed to connect the
inner capsid surface to the outer genome layer. Here, we explored mechanical properties …

Herpes virus genome, the pressure is on

DW Bauer, JB Huffman, FL Homa… - Journal of the American …, 2013 - ACS Publications
Herpes simplex virus type 1 (HSV-1) packages its micrometers-long double-stranded DNA
genome into a nanometer-scale protein shell, termed the capsid. Upon confinement within …

Mechanics of viral chromatin reveals the pressurization of human adenovirus

A Ortega-Esteban, GN Condezo, AJ Pérez-Berná… - ACS …, 2015 - ACS Publications
Tight confinement of naked genomes within some viruses results in high internal pressure
that facilitates their translocation into the host. Adenovirus, however, encodes histone-like …

Spatial mapping of the collagen distribution in human and mouse tissues by force volume atomic force microscopy

A Calò, Y Romin, R Srouji, CP Zambirinis, N Fan… - Scientific reports, 2020 - nature.com
Abstract Changes in the elastic properties of living tissues during normal development and
in pathological processes are often due to modifications of the collagen component of the …

Controlling the surface charge of simple viruses

AL Duran-Meza, MV Villagrana-Escareño… - Plos one, 2021 - journals.plos.org
The vast majority of plant viruses are unenveloped, ie, they lack a lipid bilayer that is
characteristic of most animal viruses. The interactions between plant viruses, and between …