[HTML][HTML] Emerging significance and therapeutic potential of extracellular vesicles

R Luo, M Liu, T Tan, Q Yang, Y Wang… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs), are membrane-bound vesicles that have many advantages over
traditional nanocarriers for drug and gene delivery. Evidence from recent studies indicate …

Endocannabinoid system: Role in blood cell development, neuroimmune interactions and associated disorders

DS Sharma, I Paddibhatla, S Raghuwanshi… - Journal of …, 2021 - Elsevier
The endocannabinoid system (ECS) is a complex physiological network involved in creating
homeostasis and maintaining human health. Studies of the last 40 years have shown that …

Discovery of novel fatty acid amide hydrolase (FAAH) inhibitors as anti-Alzheimer's agents through pharmacophore-based virtual screening, molecular docking and …

S Jain, S Sharma, A Paliwal, J Dwivedi… - Medicinal Chemistry …, 2024 - Springer
Alzheimer's disease (AD) is the most prevalent form of neurodegenerative condition
distinguished by the deposition of amyloid beta plaques and neurofibrillary tangles in the …

[HTML][HTML] Reactive oxygen species: Orchestrating the delicate dance of platelet life and death

R Liao, L Wang, J Zeng, X Tang, M Huang… - Redox Biology, 2025 - Elsevier
Platelets, which are vital for blood clotting and immunity, need to maintain a delicately
balanced relationship between generation and destruction. Recent studies have highlighted …

Generation of Functioning Platelets from Mature Megakaryocytes Derived from CD34+ Umbilical Cord Blood Cells

Z Zhong, C Chen, N Wang, Y Qiu, X Li… - Stem Cells and …, 2024 - liebertpub.com
Clinically patients with thrombocytopenia are in urgent need of platelet transfusion, thus it is
necessary to produce the platelets in large scale in vitro to meet the clinical needs. In this …

The progress of small molecules against cannabinoid 2 receptor (CB2R)

Q Zhang, Y Zhao, J Wu, W Zhong, W Huang, Y Pan - Bioorganic Chemistry, 2024 - Elsevier
The two subtypes of cannabinoid receptors (CBR), namely CB 1 R and CB 2 R, belong to
the G protein-coupled receptor (GPCR) superfamily and are confirmed as potential …

Low molecular weight heparin treatment reduced apoptosis and oxidative cytotoxicity in the thrombocytes of patients with recurrent pregnancy loss and thrombophilia …

Y Dal, M Nazıroğlu, MO Özkaya - Journal of Obstetrics and …, 2023 - Wiley Online Library
Aim Recurrent pregnancy loss (RPL) is known to be associated with increased
thrombophilia and oxidative toxicity. However, the mechanism of thrombophilia apoptosis …