Idiopathic inflammatory myopathies (IIM), also known as myositis, are a heterogeneous
group of autoimmune disorders with varying clinical manifestations, treatment responses …

Multiple type I interferons and interferon-γ (IFN-γ) are expressed under physiological
conditions and are increased by stress and infections, and in autoinflammatory and …

Cytokines play a central role in the pathophysiology of autoimmune and inflammatory
diseases. Several cytokines signal through the JAK-STAT pathway, which is now recognized …

Objective This open‐label 12‐week study was conducted to evaluate the efficacy and safety
of tofacitinib, a JAK inhibitor, in treatment‐refractory active dermatomyositis (DM). Methods …

Idiopathic inflammatory myopathies (IIM) are a heterogenous family of diseases that can
affect the muscles, skin, lungs, and joints. There have been prior attempts to classify IIMs …

Dermatomyositis (DM) is an idiopathic inflammatory myopathy that commonly manifests with
proximal muscle weakness and is associated with extramuscular pathology including …

Background Idiopathic inflammatory myopathy (IIM) is a multi-system autoimmune condition
characterised by muscle inflammation (myositis), interstitial lung disease (ILD), and skin …

Abstract Type I interferons (IFN-Is) are a very important group of cytokines that are produced
by innate immune cells but also act on adaptive immune cells. IFN-Is possess antiviral …

Where are we moving in the classification of idiopathic infl... : Current Opinion in Neurology
Where are we moving in the classification of idiopathic inflammatory myopathies? : Current …

The aim of the study was to summarize current knowledge on antisynthetase syndrome
(ASS), including its epidemiology, pathogenesis, proposed so far diagnostic criteria …