Next-generation sequencing technologies have revolutionarily advanced sequence-based
research with the advantages of high-throughput, high-sensitivity, and high-speed. RNA-seq …

Although gene fusions have been recognized as important drivers of cancer for decades,
our understanding of the prevalence and function of gene fusions has been revolutionized …

The diagnosis of nephrotic syndrome relies on clinical presentation and descriptive patterns
of injury on kidney biopsies, but not specific to underlying pathobiology. Consequently, there …

Fusion transcripts (ie, chimeric RNAs) resulting from gene fusions have been used
successfully for cancer diagnosis, prognosis, and therapeutic applications. In addition, many …

Ribonucleic acids (RNAs) are considered as effective and minimally invasive biomarkers for
disease diagnosis and prognosis due to their critical role in the regulation of different cellular …

Purpose To investigate oncogenic platelet-derived growth factor receptor (PDGFR) fusion
genes involvement in hematological malignancies, the advances in the PDGFR fusion …

The discovery of novel gene fusions in tumor samples has rapidly accelerated with the rise
of next-generation sequencing. A growing number of tools enable discovery of gene fusions …

Oral cancer is one of the leading malignant tumors worldwide. Despite the advent of
multidisciplinary approaches, the overall prognosis of patients with oral cancer is poor …

Overexpression of ERG in the prostate epithelium, due to chromosomal translocations,
contributes to prostate tumorigenesis. Here, genomic analysis of ERG siRNA-treated …

Background Classification of nephrotic syndrome relies on clinical presentation and
descriptive patterns of injury on kidney biopsies. This approach does not reflect underlying …