Biological network extraction from scientific literature: state of the art and challenges

C Li, M Liakata… - Briefings in …, 2014 - academic.oup.com
Networks of molecular interactions explain complex biological processes, and all known
information on molecular events is contained in a number of public repositories including the …

Bioinformatics approaches for the functional interpretation of protein lists: from ontology term enrichment to network analysis

K Laukens, S Naulaerts, WV Berghe - Proteomics, 2015 - Wiley Online Library
The main result of a great deal of the published proteomics studies is a list of identified
proteins, which then needs to be interpreted in relation to the research question and existing …

Systems biology elucidates common pathogenic mechanisms between nonalcoholic and alcoholic-fatty liver disease

S Sookoian, CJ Pirola - PLoS One, 2013 - journals.plos.org
The abnormal accumulation of fat in the liver is often related either to metabolic risk factors
associated with metabolic syndrome in the absence of alcohol consumption (nonalcoholic …

PESCADOR, a web-based tool to assist text-mining of biointeractions extracted from PubMed queries

A Barbosa-Silva, JF Fontaine, ER Donnard, F Stussi… - BMC …, 2011 - Springer
Background Biological function is greatly dependent on the interactions of proteins with
other proteins and genes. Abstracts from the biomedical literature stored in the NCBI's …

Large-scale structure of a network of co-occurring MeSH terms: statistical analysis of macroscopic properties

A Kastrin, TC Rindflesch, D Hristovski - PloS one, 2014 - journals.plos.org
Concept associations can be represented by a network that consists of a set of nodes
representing concepts and a set of edges representing their relationships. Complex …

Context-specific protein network miner–an online system for exploring context-specific protein interaction networks from the literature

R Chowdhary, SL Tan, J Zhang, S Karnik, VB Bajic… - PLoS …, 2012 - journals.plos.org
Background Protein interaction networks (PINs) specific within a particular context contain
crucial information regarding many cellular biological processes. For example, PINs may …

Text mining for protein docking

VD Badal, PJ Kundrotas, IA Vakser - PLoS computational biology, 2015 - journals.plos.org
The rapidly growing amount of publicly available information from biomedical research is
readily accessible on the Internet, providing a powerful resource for predictive biomolecular …

Literature-aided interpretation of gene expression data with the weighted global test

R Jelier, JJ Goeman, KM Hettne… - Briefings in …, 2011 - academic.oup.com
Most methods for the interpretation of gene expression profiling experiments rely on the
categorization of genes, as provided by the Gene Ontology (GO) and pathway databases …

Biomedical hypothesis generation by text mining and gene prioritization

I Petric, B Ligeti, B Gyorffy… - Protein and peptide letters, 2014 - ingentaconnect.com
Text mining methods can facilitate the generation of biomedical hypotheses by suggesting
novel associations between diseases and genes. Previously, we developed a rare-term …

TMT-HCC: A tool for text mining the biomedical literature for hepatocellular carcinoma (HCC) biomarkers identification

RAA Seoud, MS Mabrouk - Computer methods and programs in …, 2013 - Elsevier
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related mortality
worldwide. New insights into the pathogenesis of this lethal disease are urgently needed …