Cocaine: an updated overview on chemistry, detection, biokinetics, and pharmacotoxicological aspects including abuse pattern

R Roque Bravo, AC Faria, AM Brito-da-Costa, H Carmo… - Toxins, 2022 - mdpi.com
Cocaine is one of the most consumed stimulants throughout the world, as official sources
report. It is a naturally occurring sympathomimetic tropane alkaloid derived from the leaves …

Chemotaxonomy and geographical distribution of tropane alkaloids

WJ Griffin, GD Lin - Phytochemistry, 2000 - Elsevier
This review illustrates the distribution of tropane alkaloids within the families Solanaceae,
Erythroxylaceae, Proteaceae, Euphorbiaceae, Rhizophoraceae, Convolvulaceae and …

[图书][B] Karch's pathology of drug abuse

SB Karch, O Drummer - 2008 - taylorfrancis.com
Written for practitioners in the field, this critically acclaimed bestseller provides authoritative
information focused on the investigation of drug-related deaths and practical approaches to …

Elucidation of tropane alkaloid biosynthesis in Erythroxylum coca using a microbial pathway discovery platform

BG Chavez, P Srinivasan, K Glockzin… - Proceedings of the …, 2022 - National Acad Sciences
Tropane alkaloids (TAs) are heterocyclic nitrogenous metabolites found across seven orders
of angiosperms, including Malpighiales (Erythroxylaceae) and Solanales (Solanaceae) …

[HTML][HTML] Cocaine: an updated overview on chemistry, detection, biokinetics, and pharmacotoxicological aspects including abuse pattern

RR Bravo, AC Faria, AM Brito-da-Costa, H Carmo… - Toxins, 2022 - ncbi.nlm.nih.gov
Cocaine is one of the most consumed stimulants throughout the world, as official sources
report. It is a naturally occurring sympathomimetic tropane alkaloid derived from the leaves …

The tropane alkaloids

M Lounasmaa, T Tamminen - The alkaloids: chemistry and pharmacology, 1993 - Elsevier
Publisher Summary This chapter reviews tropane alkaloids and focuses in the areas of
occurrence and synthesis. The tropane alkaloids are a structurally well-defined group of …

Focused microwave‐assisted extraction of cocaine and benzoylecgonine from coca leaves

A Brachet, P Christen… - Phytochemical Analysis: An …, 2002 - Wiley Online Library
Extraction of cocaine and benzoylecgonine from coca leaves was performed by focused
microwave‐assisted extraction (FMAE). Cocaine extraction was optimised with respect to the …

Plant tropane alkaloid biosynthesis evolved independently in the Solanaceae and Erythroxylaceae

J Jirschitzka, GW Schmidt, M Reichelt… - Proceedings of the …, 2012 - National Acad Sciences
The pharmacologically important tropane alkaloids have a scattered distribution among
angiosperm families, like many other groups of secondary metabolites. To determine …

Introduction to the different classes of natural products

K Springob, TM Kutchan - Plant-derived natural products: synthesis …, 2009 - Springer
Plants produce an enormous variety of natural products with highly diverse structures. These
products are commonly termed “secondary metabolites” in contrast to the “primary …

Erythroxylum in Focus: An Interdisciplinary Review of an Overlooked Genus

DA Restrepo, E Saenz, OA Jara-Muñoz… - Molecules, 2019 - mdpi.com
The genus Erythroxylum contains species used by indigenous people of South America long
before the domestication of plants. Two species, E. coca and E. novogranatense, have been …