Thanks to recent improvements in NMR spectrometer hardware and pulse sequence design,
modern 13C NMR has become a useful tool for biomolecular applications. The complete …

Thanks to recent improvements in NMR instrumentation, pulse sequence design, and
sample preparation, a panoply of new NMR tools has become available for atomic …

Transient macromolecular complexes are often formed by protein–protein interaction
domains (eg PDZ, SH2, SH3, WW) which recognize linear sequence motifs with in vitro …

Toxin–antitoxin systems are highly abundant in plasmids and bacterial chromosomes. They
ensure plasmid maintenance by killing bacteria that have lost the plasmid. Their expression …

Contents 1. Introduction............................................................................. 33 1.1. Automated
structure determination methods in the postgenomics area.............................. 34 2. Automated …

A crucial step in determining solution structures of proteins using nuclear magnetic
resonance (NMR) spectroscopy is the process of sequential assignment, which correlates …

Although there is great interest in three-dimensional structures of glycoproteins and complex
oligosaccharides, their structural determination have been hampered by inhomogeneous …

Sequence specific resonance assignment constitutes an important step towards high-
resolution structure determination of proteins by NMR and is aided by selective identification …

Alphavirus nsP3 proteins contain long, intrinsically disordered, hypervariable domains,
HVD, which serve as hubs for interaction with many cellular proteins. Here, we have …

Carbon‐13 direct‐detection NMR methods have proved to be very useful for the
characterization of intrinsically disordered proteins (IDPs). Here we present a suite of …