WE ARE NOW ENTERING the second cen-tury in which human blood has been stored for
transfusion. In the last 2 decades of the last century, we witnessed a dramatic" paradigm …

Storage of red blood cells in preservative medium is associated with metabolic, biochemical
and molecular changes to erythrocytes collectively referred to as the “storage lesion.” In …

Several clinical studies have suggested that blood transfusions are immunosuppressive.
Whereas there have been reports describing immunosuppression induced by leukocytes or …

The sickle cell disorders (SCD) comprise homozygous sickle cell anaemia (SS), SS with~ t-
thalassaemia, sickle cell/haemoglobin C disease (SC), sickle cell/fl-thalassaemia, and other …

The substitution of glutamic acid by valine at the sixth position of the beta‐globins of
haemoglobin S (Hb S) causes a drastic reduction in the solubility of the deoxy form of Hb S …

Interventions For all experimental studies, whole blood specimens were incubated with 2
micro gram/mL of Escherichia coli endotoxin (experimental) or an equivalent volume of …

Keishi-bukuryo-gan (Gui-Zhi-Fu-Ling-Wan)(KBG) is one of the prescriptions in Japanese
traditional medicine for improving the “oketsu” syndrome, so-called blood stasis …

Materials and Methods Table 1 outlines the general characteristics of the 6 separate studies
performed. Subjects. A total of 68 subjects were studied. The volunteers (studies I, II, III, and …

Red blood cells undergo major biochemical and biomechanical changes during storage that
could effect their post transfusion performance [Hogman CF, Meryman T. Storage …

Fresh human blood was diluted 1: 5000 in buffered saline-sucrose solution and titrated to a
pH varying from 4.5 to 10.5 with 0.1 N HCl or 0.1 N NaOH. Circular regions of the membrane …