The continued global burden of malaria can in part be attributed to a complex lifecycle, with
both human hosts and mosquito vectors serving as transmission reservoirs. In preclinical …

Migration of the protozoan parasite Plasmodium through the mosquito is a complex and
delicate process, the outcome of which determines the success of malaria transmission. The …

The intracellular pathogen Legionella pneumophila subverts vesicle traffic in eukaryotic host
cells to create a vacuole that supports replication. The dot/icm genes encode a protein …

Translational repression of messenger RNAs (mRNAs) plays an important role in sexual
differentiation and gametogenesis in multicellular eukaryotes. Translational repression and …

Most proteins that coat the surface of the extracellular forms of the human malaria parasite
Plasmodium falciparum are attached to the plasma membrane via …

A novel mosquito antimicrobial peptide, gambicin, and the corresponding gene were
isolated in parallel through differential display-PCR, an expressed sequence tag (EST) …

Apicomplexan parasites critically depend on a unique form of gliding motility to colonize
their hosts and to invade cells. Gliding requires different stage and species‐specific …

An essential, but poorly understood part of malaria transmission by mosquitoes is the
development of the ookinetes into the sporozoite‐producing oocysts on the mosquito midgut …

Malaria, which is caused by Plasmodium parasites, is transmitted by anopheline
mosquitoes. When gametocytes, the precursor cells of Plasmodium gametes, are transferred …

In the past five years, there has been renewed interest in the early development of the
malaria parasite in the mosquito. Numerous exciting studies have examined in more detail …