Molecular and functional roles of microRNAs in the progression of hepatocellular carcinoma—a review

K Oura, A Morishita, T Masaki - International Journal of Molecular …, 2020 - mdpi.com
Liver cancer is the fourth leading cause of cancer deaths globally, of which hepatocellular
carcinoma (HCC) is the major subtype. Viral hepatitis B and C infections, alcohol abuse, and …

Decoding hepatocarcinogenesis from a noncoding RNAs perspective

MKA El‐Aziz, A Dawoud, CJ Kiriacos… - Journal of cellular …, 2023 - Wiley Online Library
Being a leading lethal malignancy worldwide, the pathophysiology of hepatocellular
carcinoma (HCC) has gained a lot of interest. Yet, underlying mechanistic basis of the liver …

MicroRNAs in the pathogenesis of hepatocellular carcinoma: A review

A Morishita, K Oura, T Tadokoro, K Fujita, J Tani… - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is one of the most frequently occurring
cancers, and the prognosis for late-stage HCC remains poor. A better understanding of the …

[HTML][HTML] The role of MicroRNAs in hepatocellular carcinoma

X Xu, Y Tao, L Shan, R Chen, H Jiang, Z Qian… - Journal of …, 2018 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most common cancers, leading to the second
cancer-related death in the global. Although the treatment of HCC has greatly improved over …

The long noncoding RNA HULC promotes liver cancer by increasing the expression of the HMGA2 oncogene via sequestration of the microRNA-186

Y Wang, F Chen, M Zhao, Z Yang, J Li, S Zhang… - Journal of Biological …, 2017 - ASBMB
The long noncoding RNA highly up-regulated in liver cancer (HULC) is aberrantly elevated
in hepatocellular carcinoma (HCC), and this up-regulation is crucial for HCC pathogenesis …

Exosomal microRNA-107 reverses chemotherapeutic drug resistance of gastric cancer cells through HMGA2/mTOR/P-gp pathway

L Jiang, Y Zhang, L Guo, C Liu, P Wang, W Ren - BMC cancer, 2021 - Springer
Background RNA cargo in exosomes, especially microRNAs (miRNAs), play an important
role in the chemotherapy drug resistance of human cancers. However, the role and …

microRNA 193a-5p regulates levels of nucleolar-and spindle-associated protein 1 to suppress hepatocarcinogenesis

S Roy, GJ Hooiveld, M Seehawer, S Caruso… - Gastroenterology, 2018 - Elsevier
Background & Aims We performed an integrated analysis to identify microRNAs (miRNAs)
and messenger RNAs (mRNAs) with altered expression in liver tumors from 3 mouse …

[HTML][HTML] Long non-coding RNA H19 promotes proliferation in hepatocellular carcinoma cells via H19/miR-107/CDK6 axis

A Nokkeaw, P Thamjamrassri… - Oncology …, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the leading cause of cancer death worldwide;
nevertheless, current therapeutic options are limited or ineffective for many patients …

microRNAs‐107 inhibited autophagy, proliferation, and migration of breast cancer cells by targeting HMGB1

H Ai, W Zhou, Z Wang, G Qiong… - Journal of cellular …, 2019 - Wiley Online Library
Purpose To investigate the effects of microRNAs‐107 (miR‐107) on autophagy, proliferation,
and migration of breast cancer cells and its mechanism by targeting high mobility group …

Energy stress-induced linc01564 activates the serine synthesis pathway and facilitates hepatocellular carcinogenesis

G Zhang, Y Yang, H Hu, K Liu, B Li, Y Zhu, Z Wang… - Oncogene, 2021 - nature.com
Cancer cells undergo metabolic adaption to sustain their survival and growth under
metabolic stress conditions, yet the underlying mechanism remains largely unclear. It is also …