Nanocarriers for ocular drug delivery: Current status and translational opportunity

S Gorantla, VK Rapalli, T Waghule, PP Singh… - RSC …, 2020 - pubs.rsc.org
Ocular diseases have a significant effect on vision and quality of life. Drug delivery to ocular
tissues is a challenge to formulation scientists. The major barriers to delivering drugs to the …

[HTML][HTML] Nanocrystals for enhancement of oral bioavailability of poorly water-soluble drugs

VB Junyaprasert, B Morakul - Asian journal of pharmaceutical sciences, 2015 - Elsevier
Nanocrystals, a carrier-free colloidal delivery system in nano-sized range, is an interesting
approach for poorly soluble drugs. Nanocrystals provide special features including …

[HTML][HTML] Ocular drug delivery systems: An overview

A Patel, K Cholkar, V Agrahari… - World journal of …, 2013 - ncbi.nlm.nih.gov
The major challenge faced by today's pharmacologist and formulation scientist is ocular
drug delivery. Topical eye drop is the most convenient and patient compliant route of drug …

Advanced formulation approaches for ocular drug delivery: state-of-the-art and recent patents

EB Souto, J Dias-Ferreira, A López-Machado… - Pharmaceutics, 2019 - mdpi.com
The eye presents extensive perspectives and challenges for drug delivery, mainly because
of the extraordinary capacity, intrinsic to this path, for drugs to permeate into the main …

[HTML][HTML] Application of flash nanoprecipitation to fabricate poorly water-soluble drug nanoparticles

J Tao, SF Chow, Y Zheng - Acta pharmaceutica sinica B, 2019 - Elsevier
Nanoparticles are considered to be a powerful approach for the delivery of poorly water-
soluble drugs. One of the main challenges is developing an appropriate method for …

Drug nanocrystals in the commercial pharmaceutical development process

JP Möschwitzer - International journal of pharmaceutics, 2013 - Elsevier
Nanosizing is one of the most important drug delivery platform approaches for the
commercial development of poorly soluble drug molecules. The research efforts of many …

Liquid antisolvent precipitation and stabilization of nanoparticles of poorly water soluble drugs in aqueous suspensions: Recent developments and future perspective

AA Thorat, SV Dalvi - Chemical Engineering Journal, 2012 - Elsevier
The liquid antisolvent (LAS) precipitation process for production of ultra-fine particles has
been widely researched for a last few decades. In LAS process, precipitation of solute is …

Current developments and applications of microfluidic technology toward clinical translation of nanomedicines

D Liu, H Zhang, F Fontana, JT Hirvonen… - Advanced drug delivery …, 2018 - Elsevier
Nanoparticulate drug delivery systems hold great potential for the therapy of many diseases,
especially cancer. However, the translation of nanoparticulate drug delivery systems from …

[图书][B] Handbook of encapsulation and controlled release

M Mishra - 2015 - books.google.com
Written at a level comprehensible to non-experts, this handbook covers the current state of
encapsulation and controlled released technologies, presenting the fundamental processes …

Drug nanocrystals: in vivo performances

L Gao, G Liu, J Ma, X Wang, L Zhou, X Li - Journal of controlled release, 2012 - Elsevier
Over the past few decades, there has been a considerable research interest in drug
nanocrystal system as a pharmaceutical approach for poorly soluble drugs. At the beginning …