Diuretics are drugs that promote the excretion of water and electrolytes in the body and
produce diuretic effects. Clinically, they are often used in the treatment of edema caused by …

A recent fixed combination of amlodipine (AML) besylate, olmesartan (OLM) medoxomil and
hydrochlorothiazide (HCT) has been marketed for the treatment of hypertension. The …

The mixture of hyoscine N‐butyl bromide (HBB) and ketoprofen (KTP) is commonly used for
the handling of abdominal spasms and pain relief. There are two challenges that restrict the …

Hydrochlorothiazide has been utilized clinically for the past half-century, which is popularly
known as a “water pill” as it produces increased urine output. The advancement of …

Background Hypertension is a major risk factor for the global burden of disease, and
nutrition is associated with an increased risk of mortality from multiple diseases. Few studies …

Fimasartan, amlodipine, and hydrochlorothiazide are commonly used in combination
therapies as antihypertensive drugs. This study aimed to develop and validate an analytical …

A sensitive, reproducible, robust, high-throughput ultra-performance liquid chromatography-
tandem mass spectrometry (UPLC-MS/MS) method was developed and validated for the …

The determination of the selected antihypertensive drugs in human plasma samples with the
novel solvent front position extraction (SFPE) technique is presented. The SFPE procedure …

A facile supercritical fluid chromatography method is proposed to analyse 15 co‐formulated
binary anti‐hypertensive drug combinations using a customized elution procedure. The …

The present research has established a quick and highly sensitive second‐derivative
synchronous fluorometric technique for the simultaneous quantification of a binary mixture of …