Olfactory sensory neurons (OSNs) are bipolar neurons, unusual because they turn over
continuously and have a multiciliated dendrite. The extensive changes in gene expression …

INTRODUCTION The function of the brain relies on communication among the complex
network of cells that constitute this organ. Vascularization of the central nervous system …

Animals traversing different environments encounter both stable background stimuli and
novel cues, which are thought to be detected by primary sensory neurons and then …

Building and maintaining skeletal tissue requires the activity of skeletal stem and progenitor
cells (SSPCs). Following injury, local pools of these SSPCs become active and coordinate to …

In mammalian species, including humans, the hippocampal dentate gyrus (DG) is a primary
region of adult neurogenesis. Aberrant adult hippocampal neurogenesis is associated with …

The mammalian olfactory system detects and discriminates between millions of odorants to
elicit appropriate behavioral responses. While much has been learned about how olfactory …

Veins have emerged as the origin of all other endothelial cell subtypes needed to expand
vascular networks during developmental and pathological neoangiogenesis. Here, we …

Most of the cranial sense organs of vertebrates arise from embryonic structures known as
cranial placodes. Such placodes also give rise to sensory neurons that transmit information …

ABSTRACT MEIS1 encodes a developmental transcription factor and has been linked to
restless legs syndrome (RLS) in genome-wide association studies. RLS is a movement …

In vertebrates, the embryonic olfactory epithelium contains progenitors that will give rise to
distinct classes of neurons, including olfactory sensory neurons (OSNs; involved in odor …