Glutamic acid decarboxylase (GAD) is an intracellular enzyme whose physiologic function is
the decarboxylation of glutamate to gamma-aminobutyric acid (GABA), the main inhibitory …

Objective Paraneoplastic syndromes associated with thymomas remain incompletely
understood. The objective was to examine the association between surgically resected …

Importance Little is known of glutamic acid decarboxylase antibodies (GAD-abs) in the
paraneoplastic context. Clinical recognition of such cases will lead to prompt tumor …

A number of neurological syndromes have been described in patients with positive serum
antibodies (Abs) against the enzyme glutamic acid decarboxylase (GAD), the rate limiting …

Stiff‐person syndrome (SPS) is a disorder characterized by progressive muscle rigidity with
superimposed painful muscle spasms and gait impairment due to continuous motor activity …

Failure of brainstem supranuclear centers for saccadic eye movements results in the clinical
presence of a brainstem-mediated supranuclear saccadic gaze palsy (SGP), which is …

Paraneoplastic syndromes with neuro-ophthalmologic manifestations may involve the
central nervous system, cranial nerves, neuromuscular junction, optic nerve, uvea, or retina …

Stiff person syndrome (SPS), stiff limb syndrome, jerking SPS and progressive
encephalomyelitis with rigidity and myoclonus (PERM) are a family of rare, insidiously …

The authors describe a 38-year-old woman with stiff person syndrome (SPS) and gaze-
holding nystagmus, limited abduction, vertical and horizontal ocular misalignment, deficient …

Background Patients positive for anti-glutamic acid decarboxylase 65 (GAD65) antibodies
have attracted increasing attention. Their clinical manifestations are highly heterogeneous …