T cell responses to SARS-CoV-2

A Sette, J Sidney, S Crotty - Annual review of immunology, 2023 - annualreviews.org
A large body of evidence generated in the last two and a half years addresses the roles of T
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …

Lower magnitude and faster waning of antibody responses to SARS-CoV-2 vaccination in anti-TNF-α-treated IBD patients are linked to lack of activation and …

E Garner-Spitzer, A Wagner, V Gudipati… - …, 2023 - thelancet.com
Background Patients with inflammatory bowel disease (IBD) and healthy controls received
primary SARS-CoV-2-mRNA vaccination and a booster after six months. Anti-TNF-α-treated …

Higher cell-mediated immune responses in patients with inflammatory bowel disease on anti-TNF therapy after COVID-19 vaccination

F Caldera, FA Farraye, BM Necela… - Inflammatory bowel …, 2023 - academic.oup.com
Background Some patients with inflammatory bowel disease (IBD) on immunosuppressive
therapies may have a blunted response to certain vaccines, including the messenger RNA …

[HTML][HTML] Beyond Suppression: Peripheral T Cell Responses to Vaccination in Inflammatory Bowel Disease Patients Undergoing Anti-Tumor-Necrosis-Factor Therapy

M Qui, E Salazar - Vaccines, 2024 - mdpi.com
Alimentary tract inflammation in inflammatory bowel disease (IBD) is treated by systemically
administered drugs that alter fundamental host immune responses. Biologics that target …

The MegaPool Approach to Characterize Adaptive CD4+ and CD8+ T Cell Responses

R da Silva Antunes, D Weiskopf, J Sidney… - Current …, 2023 - Wiley Online Library
Epitopes recognized by T cells are a collection of short peptide fragments derived from
specific antigens or proteins. Immunological research to study T cell responses is hindered …

Geography influences susceptibility to SARS-CoV-2 serological response in patients with inflammatory bowel disease: Multinational analysis from the ICARUS-IBD …

SY Wong, J Wellens, D Helmus… - Inflammatory Bowel …, 2023 - academic.oup.com
Background Beyond systematic reviews and meta-analyses, there have been no direct
studies of serological response to COVID-19 in patients with inflammatory bowel disease …

[HTML][HTML] mRNA-1273 vaccinated inflammatory bowel disease patients receiving TNF inhibitors develop broad and robust SARS-CoV-2-specific CD8+ T cell responses

J van den Dijssel, MC Duurland, VAL Konijn… - Journal of …, 2024 - Elsevier
Abstract SARS-CoV-2-specific CD8+ T cells recognize conserved viral peptides and in the
absence of cross-reactive antibodies form an important line of protection against emerging …

Impacts of delta and omicron variants on inactivated SARS‐CoV‐2 vaccine‐induced T cell responses in patients with autoimmune diseases and healthy controls

S Wang, J Li, S Wang, Y Ye, M Li, Y Liu… - Clinical and …, 2023 - Wiley Online Library
Background Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection
causes coronavirus disease 2019 (COVID‐19), which is still devastating economies and …

[PDF][PDF] Impact of SARS-CoV-2 vaccination in inflammatory bowel disease patients with different biological agents: a systematic review and meta-analysis

C Dai, ZY Dong, YN Wang, YH Huang, M Jiang… - Rev Esp Enferm …, 2023 - online.reed.es
Title: Impact of SARS-CoV-2 vaccination in inflammatory bowel disease patients with
different biological agents: a systematic re Page 1 Title: Impact of SARS-CoV-2 vaccination …