[HTML][HTML] Lipidomes in health and disease: Analytical strategies and considerations

F Wei, S Lamichhane, M Orešič… - TrAC Trends in Analytical …, 2019 - Elsevier
Lipidomics is a rapidly-growing field which focuses on global characterization of lipids at
molecular and systems levels. As small changes in the concentrations of lipids may have …

Mass spectrometry imaging of lipids with isomer resolution using high-pressure ozone-induced dissociation

BSR Claes, AP Bowman, BLJ Poad… - Analytical …, 2021 - ACS Publications
Mass spectrometry imaging (MSI) of lipids within tissues has significant potential for both
biomolecular discovery and histopathological applications. Conventional MSI technologies …

New frontiers in lipidomics analyses using structurally selective ion mobility-mass spectrometry

RA Harris, KL Leaptrot, JC May, JA McLean - TrAC Trends in Analytical …, 2019 - Elsevier
The growth of lipidomics and the high isomeric complexity of the lipidome has revealed a
need for analytical techniques capable of structurally characterizing lipids with a high …

Relative quantitation of unsaturated phosphatidylcholines using 193 nm ultraviolet photodissociation parallel reaction monitoring mass spectrometry

LA Macias, KY Garza, CL Feider… - Journal of the …, 2021 - ACS Publications
Structural characterization of glycerophospholipids beyond the fatty acid level has become a
major endeavor in lipidomics, presenting an opportunity to advance the understanding of the …

Ozonization of tissue sections for MALDI MS imaging of carbon–carbon double bond positional isomers of phospholipids

A Bednařík, J Preisler, D Bezdeková… - Analytical …, 2020 - ACS Publications
Visualizing the differential distribution of carbon–carbon double bond (C═ C db) positional
isomers of unsaturated phospholipids (PL) in tissue sections by use of refined matrix …

Evaluation of ultraviolet photodissociation tandem mass spectrometry for the structural assignment of unsaturated fatty acid double bond positional isomers

M Fang, Y Rustam, M Palmieri, OM Sieber… - Analytical and …, 2020 - Springer
Fatty acids are a major source of structural diversity within the lipidome due to variations in
their acyl chain lengths, branching, and cyclization, as well as the number, position, and …

Analysis of triacylglycerol and phospholipid sn‐positional isomers by liquid chromatographic and mass spectrometric methodologies

M Fabritius, B Yang - Mass Spectrometry Reviews, 2023 - Wiley Online Library
Abstract Analysis of triacylglycerol (TG) and phospholipid sn‐positional isomers can be
divided into two main categories:(a) direct separation by chromatography or other means …

Unsaturation elements and other modifications of phospholipids in bacteria: new insight from ultraviolet photodissociation mass spectrometry

MS Blevins, VK James, CM Herrera, AB Purcell… - Analytical …, 2020 - ACS Publications
Glycerophospholipids (GPLs), one of the main components of bacterial cell membranes,
exhibit high levels of structural complexity that are directly correlated with biophysical …

Accelerating Ozonolysis Reactions Using Supplemental RF-Activation of Ions in a Linear Ion Trap Mass Spectrometer

BLJ Poad, RSE Young, DL Marshall, AJ Trevitt… - Analytical …, 2022 - ACS Publications
Gas-phase ion–molecule reactions provide structural insights across a range of analytical
applications. A hindrance to the wider use of ion–molecule reactions is that they are …

Separation and identification of diacylglycerols containing branched chain fatty acids by liquid chromatography-mass spectrometry

A Palyzová, T Řezanka - Journal of Chromatography A, 2021 - Elsevier
A combination of two chromatographic and two enzymatic methods was used for the
analysis of molecular species of lipids from Gram-positive bacteria of the genus Kocuria …