The major facilitator superfamily (MFS) is the largest known superfamily of secondary active
transporters. MFS transporters are responsible for transporting a broad spectrum of …

Amino acid transporters (AATs) are membrane-bound transport proteins that mediate
transfer of amino acids into and out of cells or cellular organelles. AATs have diverse …

Abstract Background Bioactive peptides (BAPs) play a crucial physiological role in human
health. To exert their biological effects after oral administration, BAPs have to be transported …

Solute carrier (SLC) membrane transport proteins control essential physiological functions,
including nutrient uptake, ion transport, and waste removal. SLCs interact with several …

Members of the major facilitator superfamily (MFS) of transport proteins are essential for the
movement of a wide range of substrates across biomembranes. As this transport requires a …

The determination of the crystal structures of small-molecule transporters has shed light on
the conformational changes that take place during structural isomerization from outward-to …

The ancient and ubiquitous major facilitator superfamily (MFS) represents the largest
secondary transporter family and plays a crucial role in a multitude of physiological …

Owing to the development of brilliant microfocus beamlines, rapid-readout detectors and
sample changers, protein microcrystallography is rapidly becoming a popular technique for …

The NRT1/PTR family of proton-coupled transporters are responsible for nitrogen
assimilation in eukaryotes and bacteria through the uptake of peptides. However, in most …

Nitrate is a primary nutrient for plant growth, but its levels in soil can fluctuate by several
orders of magnitude. Previous studies have identified Arabidopsis NRT1. 1 as a dual-affinity …