ALCAM/CD166: A pleiotropic mediator of cell adhesion, stemness and cancer progression

F Ferragut, VS Vachetta, MF Troncoso… - Cytokine & Growth …, 2021 - Elsevier
Abstract Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) is a glycoprotein
involved in homotypic and heterotypic cell adhesion. ALCAM can be proteolytically cleaved …

[HTML][HTML] miR-214 as a key hub that controls cancer networks: small player, multiple functions

E Penna, F Orso, D Taverna - Journal of Investigative Dermatology, 2015 - Elsevier
MicroRNAs are short regulatory RNAs that are able to post-transcriptionally modulate gene
expression and that have crucial roles in the control of physiological and pathological …

The cancer paradigm of severe pulmonary arterial hypertension

PR Rai, CD Cool, JAC King, T Stevens… - American journal of …, 2008 - atsjournals.org
The plexiform lesions of severe pulmonary arterial hypertension (PAH) are similar in
histologic appearance, whether the disease is idiopathic or secondary. Both forms of the …

ALCAM/CD166: cancer-related issues

UH Weidle, D Eggle, S Klostermann… - Cancer genomics & …, 2010 - cgp.iiarjournals.org
Activated leucocyte adhesion molecule (ALCAM) was originally identified as a
transmembrane receptor which is involved in T-cell activation and has other still unresolved …

Cytoplasmic overexpression of ALCAM is prognostic of disease progression in breast cancer

M Burkhardt, E Mayordomo, KJ Winzer… - Journal of clinical …, 2006 - jcp.bmj.com
Background: Activated leucocyte cell adhesion molecule (ALCAM, CD166) is a cell surface
member of the immunoglobulin superfamily. ALCAM expression has prognostic relevance in …

Activated leukocyte cell adhesion molecule: a new paradox in cancer

SF Ofori-Acquah, JA King - Translational Research, 2008 - Elsevier
The activated leukocyte cell adhesion molecule [ALCAM/CD166/melanoma metastasis
clone D (MEMD)] is an immunoglobulin superfamily cell adhesion molecule. It is expressed …

The role of activated leukocyte cell adhesion molecule (ALCAM) in cancer progression, invasion, metastasis and recurrence: A novel cancer stem cell marker and …

B Darvishi, S Boroumandieh, K Majidzadeh-A… - … and molecular pathology, 2020 - Elsevier
Activated leukocyte cell adhesion molecule (ALCAM) or CD166 is a 100 to 105 KDa
transmembrane immunoglobulin which is involved in activation of T-cells, hematopoiesis …

Anti-CD166/4-1BB chimeric antigen receptor T cell therapy for the treatment of osteosarcoma

Y Wang, W Yu, J Zhu, J Wang, K Xia, C Liang… - Journal of Experimental & …, 2019 - Springer
Background Chimeric antigen receptor (CAR)-engineered T cells have displayed
outstanding performance in the treatment of patients with hematological malignancies …

Identification of new genes associated with breast cancer progression by gene expression analysis of predefined sets of neoplastic tissues

D Cimino, L Fuso, C Sfiligoi, N Biglia… - … journal of cancer, 2008 - Wiley Online Library
Gene expression profiles were studied by microarray analysis in 2 sets of archival breast
cancer tissues from patients with distinct clinical outcome. Seventy‐seven differentially …

Expression of transcription factor CREB1 in human breast cancer and its correlation with prognosis

A Chhabra, H Fernando, G Watkins… - Oncology …, 2007 - spandidos-publications.com
It has been suggested that the cAMP responsive element-binding protein (CREB) may act as
a transcription regulator of aromatase in breast cancer cells. However, there is little …