Chordomas are rare, malignant bone tumors of the skull-base and axial skeleton. Until
recently, there was no consensus among experts regarding appropriate clinical …

Use of proton beam therapy has expanded, with the number of proton centres rapidly
increasing not only in the USA but also worldwide. The physical characteristics of the proton …

Purpose Reirradiation of head and neck (H&N) cancer is a clinical challenge. Proton
radiation therapy (PRT) offers dosimetric advantages for normal tissue sparing and may …

Promising antitumor activities of nivolumab, a fully humanized IgG4 inhibitor antibody
against the programmed death‐1 protein, were suggested in previous phase 1 studies. The …

Purpose To evaluate the long term tumor control and toxicity of skull base tumors treated
with pencil beam scanning proton therapy (PT). Materials and methods PT was delivered to …

Proton beam radiation has been used for cancer treatment since the 1950s, but recent
increasing interest in this form of therapy and the construction of hospital-based and clinic …

Study Design. Systematic literature review. Objective. To assess the toxicity, common
radiation doses, and local control (LC) rates of radiation therapy for chordoma of the spine …

Reirradiation (reRT) for locoregional recurrences poses unique challenges and risks; re-
treatment using proton beam radiotherapy (PBT) could prove advantageous. Assessing …

Purpose To review current evidence of the role of proton therapy (PT) in other tumors than
skull base, sinusal/parasinusal, spinal and pediatric tumors; to determine medico-economic …

Purpose To report the clinical outcomes of head and neck reirradiation with proton therapy.
Methods and Materials From 2004 to 2014, 61 patients received curative-intent proton …