[HTML][HTML] Emerging concepts of miRNA therapeutics: from cells to clinic

C Diener, A Keller, E Meese - Trends in Genetics, 2022 - cell.com
MicroRNAs (miRNAs) are very powerful genetic regulators, as evidenced by the fact that a
single miRNA can direct entire cellular pathways via interacting with a broad spectrum of …

[HTML][HTML] MicroRNA let-7 and viral infections: focus on mechanisms of action

A Letafati, S Najafi, M Mottahedi, M Karimzadeh… - Cellular & Molecular …, 2022 - Springer
MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …

miRTarBase update 2022: an informative resource for experimentally validated miRNA–target interactions

HY Huang, YCD Lin, S Cui, Y Huang… - Nucleic acids …, 2022 - academic.oup.com
MicroRNAs (miRNAs) are noncoding RNAs with 18–26 nucleotides; they pair with target
mRNAs to regulate gene expression and produce significant changes in various …

[HTML][HTML] The miRNA–target interactions: An underestimated intricacy

C Diener, A Keller, E Meese - Nucleic Acids Research, 2024 - academic.oup.com
MicroRNAs (miRNAs) play indispensable roles in posttranscriptional gene regulation. Their
cellular regulatory impact is determined not solely by their sheer number, which likely …

Innovative approaches in transforming microRNAs into therapeutic tools

AFA Samad, MF Kamaroddin - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
MicroRNA (miRNA) is regarded as a prominent genetic regulator, as it can fine‐tune an
entire biological pathway by targeting multiple target genes. This characteristic makes …

The role of microRNAs in solving COVID-19 puzzle from infection to therapeutics: A mini-review

S Paul, LAB Vázquez, PR Reyes-Pérez… - Virus Research, 2022 - Elsevier
Nowadays, one of the major global health concerns is coronavirus disease 2019 (COVID-
19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Nanotechnology‐Assisted RNA Delivery: From Nucleic Acid Therapeutics to COVID‐19 Vaccines

C Rinoldi, SS Zargarian, P Nakielski, X Li… - Small …, 2021 - Wiley Online Library
In recent years, the main quest of science has been the pioneering of the groundbreaking
biomedical strategies needed for achieving a personalized medicine. Ribonucleic acids …

[HTML][HTML] Biotic stress-associated microRNA families in plants

E Šečić, KH Kogel, MJ Ladera-Carmona - Journal of Plant Physiology, 2021 - Elsevier
Plants and animals utilize various regulatory mechanisms for control of gene expression
during development in different tissues and cell types. About 30 years ago, a new …

[HTML][HTML] Circulating miRNAs as a Tool for Early Diagnosis of Endometrial Cancer—Implications for the Fertility-Sparing Process: Clinical, Biological, and Legal Aspects

R Piergentili, G Gullo, G Basile, C Gulia… - International Journal of …, 2023 - mdpi.com
This review article explores the possibility of developing an integrated approach to the
management of the different needs of endometrial cancer (EC) patients seeking to become …

Evaluation of efficacy of non-coding RNA in abiotic stress management of field crops: Current status and future prospective

S Hazra, D Moulick, A Mukherjee, S Sahib… - Plant Physiology and …, 2023 - Elsevier
Abiotic stresses are responsible for the major losses in crop yield all over the world. Stresses
generate harmful ROS which can impair cellular processes in plants. Therefore, plants have …