Ecotoxicological effects, environmental fate and risks of pharmaceutical and personal care products in the water environment: a review

H Wang, H Xi, L Xu, M Jin, W Zhao, H Liu - Science of the Total …, 2021 - Elsevier
Due to the extensive use and incomplete removal, pharmaceutical and personal care
products (PPCPs) are introduced into the water continuously. It has been proved that the …

Organic micropollutants paracetamol and ibuprofen—toxicity, biodegradation, and genetic background of their utilization by bacteria

J Żur, A Piński, A Marchlewicz… - … Science and Pollution …, 2018 - Springer
Currently, analgesics and nonsteroidal anti-inflammatory drugs (NSAIDs) are classified as
one of the most emerging group of xenobiotics and have been detected in various natural …

Occurrence of pharmaceutical, recreational and psychotropic drug residues in surface water on the northern Antarctic Peninsula region

S González-Alonso, LM Merino, S Esteban… - Environmental …, 2017 - Elsevier
Human presence in the Antarctic is increasing due to research activities and the rise in
tourism. These activities contribute a number of potentially hazardous substances. The aim …

Environmental protection by the adsorptive elimination of acetaminophen from water: a comprehensive review

CA Igwegbe, CO Aniagor, SN Oba, PS Yap… - Journal of Industrial and …, 2021 - Elsevier
Acetaminophen (ACT) is an effective and widely available analgesic and antipyretic used in
medical practice. It can get into water from veterinary use, medical waste and …

Paracetamol–toxicity and microbial utilization. Pseudomonas moorei KB4 as a case study for exploring degradation pathway

J Żur, D Wojcieszyńska, K Hupert-Kocurek… - Chemosphere, 2018 - Elsevier
Paracetamol, a widely used analgesic and antipyretic drug, is currently one of the most
emerging pollutants worldwide. Besides its wide prevalence in the literature only several …

Curative Effects of Dianthus orientalis against Paracetamol Triggered Oxidative Stress, Hepatic and Renal Injuries in Rabbit as an Experimental Model

B Ahmad, A Muhammad Yousafzai, H Maria, AA Khan… - Separations, 2023 - mdpi.com
The aim of the present study investigates the hepatoprotective, nephroprotective and
hematopoietic and antioxidant effects of Dianthus orientalis leaves aqueous extract (DO …

Toxic potential of paracetamol to freshwater organisms: a headache to environmental regulators?

B Nunes, SC Antunes, J Santos, L Martins… - … and environmental safety, 2014 - Elsevier
Paracetamol is one of the most prescribed drugs globally, due to its antipyretic and
analgesic properties. However, it is highly toxic at elevated doses, with involvement of an …

Chrysin protects rat kidney from paracetamol-induced oxidative stress, inflammation, apoptosis, and autophagy: a multi-biomarker approach

FM Kandemir, S Kucukler, E Eldutar, C Caglayan… - Scientia …, 2017 - mdpi.com
Paracetamol (PC) is a safe analgesic and antipyretic drug at therapeutic doses, and it is
widely used in clinics. However, at high doses, it can induce hepatotoxicity and …

Tangeretin alleviates cisplatin-induced acute hepatic injury in rats: targeting MAPKs and apoptosis

HA Omar, WR Mohamed, HH Arab, ESA Arafa - PLoS One, 2016 - journals.plos.org
Despite its broad applications, cisplatin affords considerable nephro-and hepatotoxicity
through triggering inflammatory and oxidative stress cascades. The aim of the current …

Environmentally relevant concentrations of oxytetracycline and copper increased liver lipid deposition through inducing oxidative stress and mitochondria dysfunction …

YH Xu, C Hogstrand, YC Xu, T Zhao, H Zheng… - Environmental …, 2021 - Elsevier
Oxytetracycline (OTC) and Cu are prevalent in aquatic ecosystems and their pollution are
issues of serious concern. The present working hypothesis is that the toxicity of Cu and OTC …