ROS-scavenging therapeutic hydrogels for modulation of the inflammatory response

YE Kim, J Kim - ACS Applied Materials & Interfaces, 2021 - ACS Publications
Although reactive oxygen species (ROS) are essential for cellular processes, excessive
ROS could be a major cause of various inflammatory diseases because of the oxidation of …

Mechanisms of melanocyte death in vitiligo

J Chen, S Li, C Li - Medicinal Research Reviews, 2021 - Wiley Online Library
Vitiligo is an autoimmune depigment disease results from extensive melanocytes
destruction. The destruction of melanocyte is thought to be of multifactorial causation …

Oxidative stress and pathophysiology of ischemic stroke: novel therapeutic opportunities

R Rodrigo, R Fernandez-Gajardo… - CNS & Neurological …, 2013 - ingentaconnect.com
Stroke is the second leading cause of death, after ischemic heart disease, and accounts for
9% of deaths worldwide. According to the World Health Organization [WHO], 15 million …

Molecular targets of oxidative stress

SV Avery - Biochemical Journal, 2011 - portlandpress.com
Aerobic life requires organisms to resist the damaging effects of ROS (reactive oxygen
species), particularly during stress. Extensive research has established a detailed picture of …

[HTML][HTML] Altered E-cadherin levels and distribution in melanocytes precede clinical manifestations of vitiligo

RY Wagner, F Luciani, M Cario-André, A Rubod… - Journal of investigative …, 2015 - Elsevier
Vitiligo is the most common depigmenting disorder resulting from the loss of melanocytes
from the basal epidermal layer. The pathogenesis of the disease is likely multifactorial and …

Polyethylenimine-coated superparamagnetic iron oxide nanoparticles impair in vitro and in vivo angiogenesis

V Mulens-Arias, JM Rojas, L Sanz-Ortega… - … , Biology and Medicine, 2019 - Elsevier
Endothelial cells are essential to tumor vascularization and impairing their activity can
potentially limit tumor growth. Since polyethylenimine (PEI)-coated superparamagnetic iron …

Mechanism of hydrogen peroxide-induced keratinocyte migration in a scratch-wound model

AEK Loo, R Ho, B Halliwell - Free Radical Biology and Medicine, 2011 - Elsevier
Recent studies have shown that low concentrations of H2O2 are produced endogenously by
nonphagocytes after wounding. We observed that H2O2 at such concentrations can …

Novel therapeutic strategies for traumatic brain injury: acute antioxidant reinforcement

R Fernández-Gajardo, JM Matamala, R Carrasco… - CNS drugs, 2014 - Springer
Traumatic brain injury (TBI) is the most important cause of disability in individuals under the
age of 45 years and thus represents a significant social and economic burden. Evidence …

Molecular and cellular basis of depigmentation in vitiligo patients

V Delmas, L Larue - Experimental dermatology, 2019 - Wiley Online Library
Vitiligo is a chronic skin disease characterized by the appearance of zones of
depigmentation. It is mostly described as an autoimmune disease in which the immune …

Receptor-Mediated Redox Imbalance: An Emerging Clinical Avenue against Aggressive Cancers

X Dai, EW Thompson, K Ostrikov - Biomolecules, 2022 - mdpi.com
Cancer cells are more vulnerable to abnormal redox fluctuations due to their imbalanced
antioxidant system, where cell surface receptors sense stress and trigger intracellular signal …