Neurovascular coupling unit dysfunction and dementia: Retinal measurements as tools to move towards population-based evidence

FCT van der Heide, TT van Sloten… - Frontiers in …, 2022 - frontiersin.org
Dysfunction of the neurovascular coupling unit may be an important contributor to dementia.
The neurovascular coupling unit comprises neuronal structures (eg astrocytes) and vascular …

The relationship between retinal layers and brain areas in asymptomatic first-degree relatives of sporadic forms of Alzheimer's disease: an exploratory analysis

I López-Cuenca, A Marcos-Dolado… - Alzheimer's Research & …, 2022 - Springer
Background Two main genetic risks for sporadic Alzheimer's disease (AD) are a family
history and ɛ4 allele of apolipoprotein E. The brain and retina are part of the central nervous …

[HTML][HTML] The association of alcohol consumption with glaucoma and related traits: findings from the UK Biobank

KV Stuart, RN Luben, AN Warwick, KM Madjedi… - Ophthalmology …, 2023 - Elsevier
Purpose To examine the associations of alcohol consumption with glaucoma and related
traits, to assess whether a genetic predisposition to glaucoma modified these associations …

Retinal thinning in adults with autism spectrum disorder

EBN Friedel, L Tebartz van Elst, M Schäfer… - Journal of Autism and …, 2024 - Springer
Since the retina shares its embryological origin with the central nervous system, optical
coherence tomography (OCT), an imaging technique frequently employed in ophthalmology …

Use of artificial intelligence algorithms to predict systemic diseases from retinal images

R Khan, J Surya, M Roy… - … : Data Mining and …, 2023 - Wiley Online Library
The rise of non‐invasive, rapid, and widely accessible quantitative high‐resolution imaging
methods, such as modern retinal photography and optical coherence tomography (OCT) …

Eye-brain connections revealed by multimodal retinal and brain imaging genetics

B Zhao, Y Li, Z Fan, Z Wu, J Shu, X Yang… - Nature …, 2024 - nature.com
The retina, an anatomical extension of the brain, forms physiological connections with the
visual cortex of the brain. Although retinal structures offer a unique opportunity to assess …

[HTML][HTML] Association between polygenic risk for schizophrenia and retinal morphology: A cross-sectional analysis of the United Kingdom Biobank

BA Blose, SM Silverstein, KV Stuart, PA Keane… - Psychiatry …, 2024 - Elsevier
We examined the relationship between genetic risk for schizophrenia (SZ), using polygenic
risk scores (PRSs), and retinal morphological alterations. Retinal structural and vascular …

Association of retinal nerve layers thickness and brain imaging in healthy young subjects from the i‐Share‐Bordeaux study

SC Lima Rebouças, F Crivello, A Tsuchida… - Human Brain …, 2023 - Wiley Online Library
Given the anatomical and functional similarities between the retina and the brain, the retina
could be a “window” for viewing brain structures. We investigated the association between …

Retinal microvasculature and imaging markers of brain frailty in normal aging adults

W Tao, WR Kwapong, J Xie, Z Wang, X Guo… - Frontiers in Aging …, 2022 - frontiersin.org
Background The retina and brain share a similar embryologic origin, blood barriers, and
microvasculature features. Thus, retinal imaging has been of interest in the aging population …

Retinal nerve fiber layer thinning as a novel fingerprint for cardiovascular events: results from the prospective cohorts in UK and China

Y Chen, Y Yuan, S Zhang, S Yang, J Zhang, X Guo… - BMC medicine, 2023 - Springer
Background Retinal structural abnormalities have been found to serve as biomarkers for
cardiovascular disease (CVD). However, the association between retinal nerve fiber layer …