Nanoemulsion as pharmaceutical carrier for dermal and transdermal drug delivery: Formulation development, stability issues, basic considerations and applications

VK Rai, N Mishra, KS Yadav, NP Yadav - Journal of controlled release, 2018 - Elsevier
The use of nanoemulsion in augmenting dermal and transdermal effectiveness of drugs has
now well established. The development of nanoemulsion based semisolid dosage forms is …

Nanoemulsion: A review on mechanisms for the transdermal delivery of hydrophobic and hydrophilic drugs

DS Shaker, RAH Ishak, A Ghoneim… - Scientia Pharmaceutica, 2019 - mdpi.com
Nanoemulsions (NEs) are colloidal dispersions of two immiscible liquids, oil and water, in
which one is dispersed in the other with the aid of a surfactant/co-surfactant mixture, either …

Current insights on antifungal therapy: Novel nanotechnology approaches for drug delivery systems and new drugs from natural sources

F Sousa, D Ferreira, S Reis, P Costa - Pharmaceuticals, 2020 - mdpi.com
The high incidence of fungal infections has become a worrisome public health issue, having
been aggravated by an increase in host predisposition factors. Despite all the drugs …

Nanoemulsions—advances in formulation, characterization and applications in drug delivery

SA Chime, FC Kenechukwu… - … of nanotechnology in drug …, 2014 - books.google.com
An ideal drug delivery system fulfils the objective of maximizing therapeutic effect while
minimizing toxicity. With the progress in time and advances in science and technology …

Preparation, characterization and in vitro release kinetics of clozapine solid lipid nanoparticles

V Venkateswarlu, K Manjunath - Journal of controlled release, 2004 - Elsevier
Clozapine, a lipophilic antipsychotic drug, has very poor oral bioavailability (< 27%) due to
first pass effect. Solid lipid nanoparticle (SLN) delivery systems of clozapine have been …

Electron microscopy of nanoemulsions: An essential tool for characterisation and stability assessment

V Klang, NB Matsko, C Valenta, F Hofer - Micron, 2012 - Elsevier
The characterisation of pharmaceutical formulations by microscopic techniques is essential
to obtain reliable data about the actual morphology of the system. Since the size range of …

Lipid nanoparticles as vehicles for topical psoralen delivery: solid lipid nanoparticles (SLN) versus nanostructured lipid carriers (NLC)

JY Fang, CL Fang, CH Liu, YH Su - European Journal of Pharmaceutics …, 2008 - Elsevier
Solid lipid nanoparticles (SLN) were developed by using Precirol ATO 5 as the solid core of
the particles for topical psoralen delivery. Nanostructured lipid carriers (NLC) consisting of …

Nanocarrier-based topical drug delivery for the treatment of skin diseases

M Gupta, U Agrawal, SP Vyas - Expert opinion on drug delivery, 2012 - Taylor & Francis
Introduction: Skin disorders will continue to cause complications in patients. At present, there
is an expansion of research into dermatologic treatment due to a critical need for new …

Studies on the formation of O/W nano-emulsions, by low-energy emulsification methods, suitable for pharmaceutical applications

N Sadurní, C Solans, N Azemar… - European Journal of …, 2005 - Elsevier
The formation of O/W nano-emulsions suitable for pharmaceutical application and the
solubilisation of a practically non-water-soluble drug, lidocaine, have been studied in …

Hydrogel-thickened nanoemulsion system for topical delivery of lipophilic drugs

D Mou, H Chen, D Du, C Mao, J Wan, H Xu… - International Journal of …, 2008 - Elsevier
In this work, a hydrogel-thickened nanoemulsion system (HTN) with powerful permeation
ability, good stability and suitable viscosity was investigated for topical delivery of active …