[HTML][HTML] Guts imbalance imbalances the brain: a review of gut microbiota association with neurological and psychiatric disorders
In the last ten years, there has been a growing interest regarding the relationship between
gut microbiota, brain, and neurological-associated affections. As multiple preclinical and …
gut microbiota, brain, and neurological-associated affections. As multiple preclinical and …
Genetics of human brain development
Brain development in humans is achieved through precise spatiotemporal genetic control,
the mechanisms of which remain largely elusive. Recently, integration of technological …
the mechanisms of which remain largely elusive. Recently, integration of technological …
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-
wide association study of 41,917 bipolar disorder cases and 371,549 controls of European …
wide association study of 41,917 bipolar disorder cases and 371,549 controls of European …
New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications
Psychiatric genetics has made substantial progress in the last decade, providing new
insights into the genetic etiology of psychiatric disorders, and paving the way for precision …
insights into the genetic etiology of psychiatric disorders, and paving the way for precision …
Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy
G Hindley, AA Shadrin, D van der Meer… - Nature human …, 2023 - nature.com
Personality and cognitive function are heritable mental traits whose genetic foundations may
be distributed across interconnected brain functions. Previous studies have typically treated …
be distributed across interconnected brain functions. Previous studies have typically treated …
[HTML][HTML] Antipsychotic polypharmacy for the management of schizophrenia: evidence and recommendations
M Lähteenvuo, J Tiihonen - Drugs, 2021 - Springer
Schizophrenia is a debilitating illness with a lifetime prevalence estimate of 0.6% and
consists of symptoms from the positive, negative, and cognitive domains. Social support …
consists of symptoms from the positive, negative, and cognitive domains. Social support …
Genetic association between schizophrenia and cortical brain surface area and thickness
Importance Schizophrenia is a complex heritable disorder associated with many genetic
variants, each with a small effect. While cortical differences between patients with …
variants, each with a small effect. While cortical differences between patients with …
[HTML][HTML] Schizophrenia genomics: convergence on synaptic development, adult synaptic plasticity, or both?
J Hall, NJ Bray - Biological Psychiatry, 2022 - Elsevier
Large-scale genomic studies of schizophrenia have identified hundreds of genetic loci
conferring risk to the disorder. This progress offers an important route toward defining the …
conferring risk to the disorder. This progress offers an important route toward defining the …
[HTML][HTML] Grey and white matter microstructure is associated with polygenic risk for schizophrenia
Recent discovery of approximately 270 common genetic variants associated with
schizophrenia has enabled polygenic risk scores (PRS) to be measured in the population …
schizophrenia has enabled polygenic risk scores (PRS) to be measured in the population …
Shared genetic architecture between schizophrenia and subcortical brain volumes implicates early neurodevelopmental processes and brain development in …
Patients with schizophrenia have consistently shown brain volumetric abnormalities,
implicating both etiological and pathological processes. However, the genetic relationship …
implicating both etiological and pathological processes. However, the genetic relationship …