Bioprinting is rapidly being adopted as a major method for fabricating tissue engineering
constructs. Through the precise deposition of cell-and bioactive molecule-laden materials …

The need for bone grafts is tremendous, and that leads to the use of autograft, allograft, and
bone graft substitutes. The biology of the bone is quite complex regarding cellular …

Osteochondral repair remains a major challenge in current clinical practice despite
significant advances in tissue engineering. In particular, the lateral integration of …

Fabrication of anisotropic osteochondral-mimetic scaffold with mineralized subchondral
zone and gradient interface remains challenging. We have developed an injectable semi …

Pores play a crucial role in bone regeneration as they allow the exchange of nutrition and
oxygen, expulsion of waste products, and bone tissue and vascular ingrowth through the …

Regenerated silk fibroin (RSF) of Bombyx mori silk fiber is a promising natural material for
bone defect repair. However, a lack of specific integrin and growth factor for osteoinduction …

Articular cartilage is a highly specialised connective tissue of diarthrodial joints which
provides a smooth, lubricated surface for joint articulation and plays a crucial role in the …

Osteochondral (OC) regeneration faces several limitations in orthopedic surgery, owing to
the complexity of the OC tissue that simultaneously entails the restoration of articular …

Osteochondral tissue engineering has become a promising strategy for repairing focal
chondral lesions and early osteoarthritis (OA), which account for progressive joint pain and …

Regenerating chondral and osteochondral injuries is a main challenge in orthopedics.
Some therapeutic strategies such as joint preservation operations, non-operative …