In this review, we discuss all sulfur-containing FDA-approved drugs and their structures. The
second section of the review is dedicated to structural analysis and is divided into 14 …

Abstract (C–X–C motif) ligand (CXCL) 10 (CXCL10) belongs to the ELR− CXC subfamily
chemokine. CXCL10 exerts its function through binding to chemokine (C–X–C motif) …

Immunotherapy using anti-programmed death 1 ligand 1 (PD-L1) antibodies has shown
clinical efficacy against hepatocellular carcinoma (HCC) and is recognized as the first-line …

The chemokine receptor CXCR3 and its chemokines CXCL9, CXCL10, and CXCL11 are
involved in the pathogenesis of autoimmune diseases. Th1 lymphocytes are recruited by …

Interferon (IFN) γ-induced protein 10kDa (IP-10) or CXC motif chemokine 10 (CXCL10) is a
small cytokine belonging to the CXC chemokine family. This family of signaling molecules is …

Abstract Introduction Angiotensin-converting-enzyme-2 (ACE-2) was demonstrated to be the
receptor for cellular entry of SARS-CoV-2. ACE-2 mRNA was identified in several human …

A Th1 immune-preponderance has been shown in the immunopathogenesis of autoimmune
thyroiditis (AT), Graves' disease (GD) and Graves' Ophthalmopathy (GO), in which the Th1 …

Context: CXC α-chemokine CXCL10/IP-10 plays an important role in the initial phases of
Graves' ophthalmopathy (GO). Human thyrocytes, orbital fibroblasts, and preadipocytes are …

Background Chemokines contribute to the pathogenesis of autoimmune hepatitis by
directing the migration and positioning of inflammatory and immune cells within the liver …

Inflammatory myopathies (IMs) are systemic diseases characterized by a T helper (Th) 1
type inflammatory response and cell infiltrates within skeletal muscles. The mainstay of …