Quantitative phase imaging techniques for the study of cell pathophysiology: from principles to applications

KR Lee, K Kim, J Jung, JH Heo, S Cho, S Lee… - Sensors, 2013 - mdpi.com
A cellular-level study of the pathophysiology is crucial for understanding the mechanisms
behind human diseases. Recent advances in quantitative phase imaging (QPI) techniques …

Intracellular cAMP sensor EPAC: physiology, pathophysiology, and therapeutics development

WG Robichaux III, X Cheng - Physiological reviews, 2018 - journals.physiology.org
This review focuses on one family of the known cAMP receptors, the exchange proteins
directly activated by cAMP (EPACs), also known as the cAMP-regulated guanine nucleotide …

Review of quantitative phase-digital holographic microscopy: promising novel imaging technique to resolve neuronal network activity and identify cellular biomarkers …

P Marquet, C Depeursinge, PJ Magistretti - Neurophotonics, 2014 - spiedigitallibrary.org
Quantitative phase microscopy (QPM) has recently emerged as a new powerful quantitative
imaging technique well suited to noninvasively explore a transparent specimen with a …

[HTML][HTML] ATP and its metabolite adenosine as regulators of dendritic cell activity

C Silva-Vilches, S Ring, K Mahnke - Frontiers in immunology, 2018 - frontiersin.org
Adenosine (Ado) is a well-studied neurotransmitter, but it also exerts profound immune
regulatory functions. Ado can (i) actively be released by various cells into the tissue …

Profiling individual human red blood cells using common-path diffraction optical tomography

Y Kim, H Shim, K Kim, HJ Park, S Jang, YK Park - Scientific reports, 2014 - nature.com
Due to its strong correlation with the pathophysiology of many diseases, information about
human red blood cells (RBCs) has a crucial function in hematology. Therefore, measuring …

Real-time visualization of 3-D dynamic microscopic objects using optical diffraction tomography

K Kim, KS Kim, HJ Park, JC Ye, YK Park - Optics express, 2013 - opg.optica.org
3-D refractive index (RI) distribution is an intrinsic bio-marker for the chemical and structural
information about biological cells. Here we develop an optical diffraction tomography …

Regulatory T-cell-mediated suppression of conventional T-cells and dendritic cells by different cAMP intracellular pathways

CM Rueda, CM Jackson, CA Chougnet - Frontiers in immunology, 2016 - frontiersin.org
Regulatory T-cells (Tregs) mediate their suppressive action by acting directly on
conventional T-cells (Tcons) or dendritic cells (DCs). One mechanism of Treg suppression is …

Dynamic spectroscopic phase microscopy for quantifying hemoglobin concentration and dynamic membrane fluctuation in red blood cells

Y Jang, J Jang, YK Park - Optics express, 2012 - opg.optica.org
We report a technique for simultaneous label-free quantification of cytoplasmic hemoglobin
Hb concentration and dynamic membrane fluctuation in individual red blood cells (RBCs) …

Hyper-progressive disease: the potential role and consequences of T-regulatory cells foiling anti-PD-1 cancer immunotherapy

C Tay, Y Qian, S Sakaguchi - Cancers, 2020 - mdpi.com
Simple Summary Since immune cells were found to attack cancer cells, strategies have
been developed to sustain anti-cancer immune functions to prevent them from becoming …

PGE2 differentially regulates monocyte-derived dendritic cell cytokine responses depending on receptor usage (EP2/EP4)

NJ Poloso, P Urquhart, A Nicolaou, J Wang… - Molecular …, 2013 - Elsevier
Dendritic cells (DCs) are central players in coordinating immune responses, both innate and
adaptive. While the role of lipid mediators in the immune response has been the subject of …