[PDF][PDF] RETRACTED: Harnessing TRAIL-Induced Apoptosis Pathway for Cancer Immunotherapy and Associated Challenges

E Razeghian, W Suksatan… - Frontiers in …, 2021 - frontiersin.org
The immune cytokine tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has
attracted rapidly evolving attention as a cancer treatment modality because of its …

Melatonin: an important anticancer agent in colorectal cancer

M Mirza‐Aghazadeh‐Attari… - Journal of cellular …, 2020 - Wiley Online Library
Colorectal cancer is one of the most common cancers among the elderly, which is also seen
in the forms of hereditary syndromes occurring in younger individuals. Numerous studies …

Curcumol overcomes TRAIL resistance of non‐small cell lung cancer by targeting NRH: quinone oxidoreductase 2 (NQO2)

J Zhang, Y Zhou, N Li, WT Liu, JZ Liang… - Advanced …, 2020 - Wiley Online Library
Resistance to tumor‐necrosis‐factor‐related apoptosis‐inducing ligand (TRAIL) of cancer
cell remains a key obstacle for clinical cancer therapies. To overcome TRAIL resistance, this …

Anticancer molecular mechanisms of oleocanthal

M El Haouari, JE Quintero… - Phytotherapy Research, 2020 - Wiley Online Library
Cancer is among the leading causes of mortality worldwide. Current cancer therapies are
associated with serious side effects, which further damage patients' health. Therefore, the …

A scientometric visualization analysis for natural products on cancer research from 2008 to 2020

H Chen, R Li, F Zhang, Q Yao, Y Guo - Frontiers in pharmacology, 2021 - frontiersin.org
Background: An increasing number of studies have shown that natural products have anti-
tumor effects, and it has become a hotspot in cancer research. However, few bibliometric …

[HTML][HTML] Anastatica hierochuntica (L.) methanolic and aqueous extracts exert antiproliferative effects through the induction of apoptosis in MCF-7 breast cancer cells

S Rameshbabu, SA Messaoudi, ZI Alehaideb… - Saudi Pharmaceutical …, 2020 - Elsevier
Breast cancer therapy using anticancer bioactive compounds derived from natural products
as adjuvant treatment has gained recognition due to expensive and toxic conventional …

Pentagalloyl glucose inhibits TNF‐α‐activated CXCL1/GRO-α expression and induces apoptosis‐related genes in triple-negative breast cancer cells

P Mendonca, S Alghamdi, S Messeha, KFA Soliman - Scientific Reports, 2021 - nature.com
In triple-negative breast cancer (TNBC), the tumor microenvironment is associated with
increased proliferation, suppressing apoptotic mechanisms, an altered immune response …

Anticancer mechanism of artonin E and related prenylated flavonoids from the medicinal plant Artocarpus elasticus

C Bailly - Asian Journal of Natural Product Biochemistry, 2021 - smujo.id
Bailly C. 2021. Anticancer mechanism of artonin E and related prenylated flavonoids from
the medicinal plant Artocarpus elasticus. Asian J Nat Prod Biochem 19: 45-57. Plants of the …

Andrographolide elevates tumor necrosis factor-related apoptosis-inducing ligand lethality through reactive oxygen species accumulation and gasdermin E cleavage …

Y Wang, D Huang, T Song, X Qi, M Li, H Zhang, Y Liu… - Medical Oncology, 2022 - Springer
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is selectively lethal to
cancer cells and harmless to normal cells, making it a potential agent for cancer therapy …

A Comprehensive Insight into Apoptosis: Molecular Mechanisms, Signaling Pathways, and Modulating Therapeutics

M Mosadegh, N Noori Goodarzi, Y Erfani - Cancer Investigation, 2025 - Taylor & Francis
Apoptosis, or programmed cell death, is a fundamental biological process essential for
maintaining tissue homeostasis. Dysregulation of apoptosis is implicated in a variety of …