Gene therapy is a promising new technique for treating many serious incurable diseases,
such as cancer and genetic disorders. The main problem limiting the application of this …

This review offers a critical analysis of the state of the art of medical microbubbles and their
application in therapeutic delivery and monitoring. When driven by an ultrasonic pulse …

Ultrasound exposure (USE) in the presence of microbubbles (MCB)(eg contrast agents used
to enhance ultrasound imaging) increases plasmid transfection efficiency in vitro by several …

Besides its broad application in research and biotechnology, genome editing (GE) has great
potential for clinical gene therapy, but delivery of GE tools remains a bottleneck. Whereas …

Gene delivery as a promising and valid tool has been used for treating many serious
diseases that conventional drug therapies cannot cure. Due to the advancement of physical …

Microbubble ultrasound contrast agents have the potential to dramatically improve gene
therapy treatments by enhancing the delivery of therapeutic DNA to malignant tissue. The …

Many thousands of contrast ultrasound studies have been conducted in clinics around the
world. In addition, the microbubbles employed in these examinations are being widely …

Kidney disease is a leading cause of morbidity and mortality across the globe. Current
interventions for kidney disease include dialysis and renal transplantation, which have …

Originally developed as contrast agents for ultrasound imaging and diagnostics, in the past
years, microbubbles have made their way back from the patients' bedside to the researcher's …

Ultrasound is a very effective modality for drug delivery and gene therapy because energy
that is non-invasively transmitted through the skin can be focused deeply into the human …