Increasing evidence from epidemiological, clinical and experimental studies indicate that
age-related cerebromicrovascular dysfunction and microcirculatory damage play critical …

Derangements in cerebrovascular structure and function can impair cognitive performance
throughout ageing and in cardiometabolic disease states, thus increasing dementia risk …

Sex is an important determinant of brain microvessels (MVs) function and susceptibility to
cerebrovascular and neurological diseases, but underlying mechanisms are unclear. Using …

Sex differences exist in how cerebral blood vessels function under both physiological and
pathological conditions, contributing to observed sex differences in risk and outcomes of …

Cerebrovascular reactivity (CVR), is important for determining future risk of cerebrovascular
disease. It is unclear if primary aging is associated with reductions in CVR because previous …

The incidence of cardiovascular disease (CVD) is lower in premenopausal women but
increases with age and menopause compared with similarly aged men. Based on the …

Abstract Thromboxane A 2 (TxA 2) plays a very important role in various cardiovascular
diseases through its action on platelet aggregation, vasoconstriction, and proliferation. The …

Cerebrovascular diseases, such as ischemic cerebral vascular accident (CVA), are
responsible for causing high rates of morbidity, mortality, and disability in the population …

Premenopausal women have a lower incidence of cardiovascular disease (CVD) compared
with their age-matched male counterparts; however, this discrepancy is abolished following …

Gender-affirming hormone replacement therapy (gaHRT) is an important step for many in
the gender diverse community, associated with increased quality-of-life and lower self …