Elongation of N6-benzyladenosine scaffold via Pd-catalyzed C–C bond formation leads to derivatives with antiflaviviral activity
AA Zenchenko, MS Drenichev, EV Khvatov… - Bioorganic & Medicinal …, 2024 - Elsevier
Decoration of nucleoside analogues with lipophilic groups often leads to compounds with
improved antiviral activity. For example, N 6-benzyladenosine derivatives containing …
improved antiviral activity. For example, N 6-benzyladenosine derivatives containing …
Phenotypic assessment of antiviral activity for spiro‐annulated oxepanes and azepenes
DI Osolodkin, LI Kozlovskaya… - Chemical Biology & …, 2024 - Wiley Online Library
Evolutionary potential of viruses can result in outbreaks of well‐known viruses and
emergence of novel ones. Pharmacological methods of intervening the reproduction of …
emergence of novel ones. Pharmacological methods of intervening the reproduction of …
Rimantadine derivatives with antiviral activity against flaviviruses and rimantadine-resistant strain of influenza A virus
NA Zefirov, EV Khvatov, EV Nurieva… - Russian Chemical …, 2024 - Springer
Pyridine-containing amides of rimantadine (1-(1-adamantyl) ethylamine) were synthesized
by the amidation of rimantadine hydrochloride by the corresponding acids in the NEt3—N …
by the amidation of rimantadine hydrochloride by the corresponding acids in the NEt3—N …
[3+2] Cycloaddition of N‐benzylazomethine Methylide with Various Arylidene‐Azolones
IV Tiushina, AI Sokolov, AY Smirnov… - …, 2024 - Wiley Online Library
Spirocyclic skeletons are highly attractive for design of biologically active compounds.[3+ 2]
Cycloaddition of N‐benzylazomethine methylide with various arylidene‐azolones achieve to …
Cycloaddition of N‐benzylazomethine methylide with various arylidene‐azolones achieve to …
Stereo-dependent nucleophilic ring-opening of 1,6,10,14-tetraoxatetraspiro[2.1.25.1.29.1.213.13]hexadecane upon treatment with sodium azide
KN Sedenkova, DV Savchenkova… - Russian Chemical …, 2024 - Springer
Abstract Nucleophilic ring-opening of 1, 6, 10, 14-tetraoxatetraspiro [2.1. 25.1. 29.1. 213.13]
hexadecane, a cyclooctane structure spiro-fused with four oxirane fragments, under the …
hexadecane, a cyclooctane structure spiro-fused with four oxirane fragments, under the …