Molecular mechanisms and risk factors for the pathogenesis of hydrocephalus

J Li, X Zhang, J Guo, C Yu, J Yang - Frontiers in Genetics, 2022 - frontiersin.org
Hydrocephalus is a neurological condition due to the aberrant circulation and/or obstruction
of cerebrospinal fluid (CSF) flow with consequent enlargement of cerebral ventricular …

Anthropomorphic model of intrathecal cerebrospinal fluid dynamics within the spinal subarachnoid space: spinal cord nerve roots increase steady-streaming

M Khani, LR Sass, T Xing… - Journal of …, 2018 - asmedigitalcollection.asme.org
Cerebrospinal fluid (CSF) dynamics are thought to play a vital role in central nervous system
(CNS) physiology. The objective of this study was to investigate the impact of spinal cord …

[PDF][PDF] Cerebrospinal fluid biomarkers in idiopathic normal pressure hydrocephalus

XJ Zhang, J Guo, J Yang - Neuroimmunology and …, 2020 - pdfs.semanticscholar.org
Idiopathic normal pressure hydrocephalus (iNPH) is characterized by abnormal
cerebrospinal fluid (CSF) flow and consequent cerebral ventricular enlargement due to …

A novel model of acquired hydrocephalus for evaluation of neurosurgical treatments

JP McAllister, MR Talcott, AM Isaacs, SH Zwick… - Fluids and Barriers of …, 2021 - Springer
Background Many animal models have been used to study the pathophysiology of
hydrocephalus; most of these have been rodent models whose lissencephalic cerebral …

The “glymphatic-lymphatic system pathology” and a new categorization of neurodegenerative disorders

P Gallina, C Nicoletti, A Scollato, F Lolli - Frontiers in Neuroscience, 2021 - frontiersin.org
Neurodegeneration is the ultimate manifestation of various neurodegenerative,
neurovascular, and neuroinflammatory diseases, brain traumatisms, and aging. However …

A soft robotic actuator system for in vivo modeling of normal pressure hydrocephalus

F Flürenbrock, L Rosalia, A Podgoršak… - IEEE transactions on …, 2023 - ieeexplore.ieee.org
Objective: The intracranial pressure (ICP) affects the dynamics of cerebrospinal fluid (CSF)
and its waveform contains information that is of clinical importance in medical conditions …

Wearable intracranial pressure monitoring sensor for infants

B Zhang, Z Huang, H Song, HS Kim, J Park - Biosensors, 2021 - mdpi.com
Monitoring of intracranial pressure (ICP) is important for patients at risk of raised ICP, which
may indicate developing diseases in brains that can lead to brain damage or even death …

Modifying the ICP pulse wave: effects on parenchymal blood flow pulsatility

S Qvarlander, SM Dombrowski… - Journal of Applied …, 2023 - journals.physiology.org
Pulsation of the cerebral blood flow (CBF) produces intercranial pressure (ICP) waves. The
aim of this study is to determine whether externally modifying ICP pulsatility alters …

Toward the “Perfect” Shunt: Historical Vignette, Current Efforts, and Future Directions

A Podgoršak, F Flürenbrock, NE Trimmel… - Advances and Technical …, 2024 - Springer
As a concept, drainage of excess fluid volume in the cranium has been around for more than
1000 years. Starting with the original decompression-trepanation of Abulcasis to modern …

Cerebral blood flow augmentation using a cardiac-gated intracranial pulsating balloon pump in a swine model of elevated ICP

O Doron, T Or, L Battino, G Rosenthal… - Journal of …, 2019 - thejns.org
OBJECTIVE Augmenting brain perfusion or reducing intracranial pressure (ICP) dose is the
end target of many therapies in the neuro-critical care unit. Many present therapies rely on …