PINK1 controls RTN3L-mediated ER autophagy by regulating peripheral tubule junctions

R Chidambaram, K Kumar, S Parashar… - Journal of Cell …, 2024 - rupress.org
Here, we report that the RTN3L–SEC24C endoplasmic reticulum autophagy (ER-phagy)
receptor complex, the CUL3KLHL12 E3 ligase that ubiquitinates RTN3L, and the FIP200 …

Less is better: various means to reduce protein load in the endoplasmic reticulum

S Dabsan, G Twito, S Biadsy, A Igbaria - The FEBS Journal, 2024 - Wiley Online Library
The endoplasmic reticulum (ER) is an important organelle that controls the intracellular and
extracellular environments. The ER is responsible for folding almost one‐third of the total …

The p24-family member, TMED9, coordinates clearance of misfolded GPI-anchored proteins from the ER to the Golgi via the Rapid ER Stress-Induced Export pathway

E Ronzier, P Satpute-Krishnan - bioRxiv, 2024 - biorxiv.org
The p24-family member TMED9 has recently emerged as a player in secretory pathway
protein quality control (PQC) that influences the trafficking and degradation of misfolded …