Quantifying supercoiling-induced denaturation bubbles in DNA

J Adamcik, JH Jeon, KJ Karczewski, R Metzler… - Soft Matter, 2012 - pubs.rsc.org
In both eukaryotic and prokaryotic DNA sequences of 30–100 base-pairs rich in AT base-
pairs have been identified at which the double helix preferentially unwinds. Such DNA …

Mixed order transition and condensation in an exactly soluble one dimensional spin model

A Bar, D Mukamel - Journal of Statistical Mechanics: Theory and …, 2014 - iopscience.iop.org
Mixed order phase transitions (MOT), which display discontinuous order parameter and
diverging correlation length, appear in several seemingly unrelated settings ranging from …

Origins of biological function in DNA and RNA hairpin loop motifs from replica exchange molecular dynamics simulation

JB Swadling, K Ishii, T Tahara, A Kitao - Physical Chemistry Chemical …, 2018 - pubs.rsc.org
Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) have remarkably similar chemical
structures, but despite this, they play significantly different roles in modern biology. In this …

Localization, big-jump regime and the effect of disorder for a class of generalized pinning models

G Giacomin, B Havret - Journal of Statistical Physics, 2020 - Springer
One dimensional pinning models have been widely studied in the physical and
mathematical literature, also in presence of disorder. Roughly speaking, they undergo a …

Macroscopic loop formation in circular DNA denaturation

A Kabakçıoğlu, A Bar, D Mukamel - … Review E—Statistical, Nonlinear, and Soft …, 2012 - APS
The statistical mechanics of DNA denaturation under fixed linking number is qualitatively
different from that of unconstrained DNA. Quantitatively different melting scenarios are …

Spatial complexity in nature, science and technology

F Papadimitriou, F Papadimitriou - Spatial complexity: Theory …, 2020 - Springer
Some characteristic domains of science and technology for which spatial complexity is
significant are examined here. In cosmology, spatial complexity relates to the large-scale …

Denaturation of circular DNA: supercoils and overtwist

A Bar, A Kabakçıoğlu, D Mukamel - … Review E—Statistical, Nonlinear, and Soft …, 2012 - APS
The denaturation transition of circular DNA is studied within a Poland-Scheraga-type
approach, generalized to account for the fact that the total linking number (LK), which …

The rubber band revisited: Wang–Landau simulation

LS Ferreira, AA Caparica, MA Neto… - Journal of Statistical …, 2012 - iopscience.iop.org
In this work we apply Wang–Landau simulations to a simple model which has exact
solutions both in the microcanonical and canonical formalisms. The simulations were carried …

Purification of Recombinant E. Coli Topoisomerase III for Structure-Based Drug Design Using Protein Crystallization

MA Perez Rodriguez… - FIU Undergraduate …, 2024 - digitalcommons.fiu.edu
Type IA Topoisomerases are ubiquitous enzymes found throughout all life forms and
species. These topoisomerases relieve the topographical constrains formed by DNA during …

Constrained thermal denaturation of DNA under fixed linking number

A Bar, A Kabakçıoğlu, D Mukamel - Central European Journal of Physics, 2012 - Springer
A DNA molecule with freely fluctuating ends undergoes a sharp thermal denaturation
transition upon heating. However, in circular DNA chains and some experimental setups that …