The novel corona virus termed severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has spread throughout the globe at a formidable speed, causing tens of millions of …

Vaccine development utilizing various platforms is one of the strategies that has been
proposed to address the coronavirus disease 2019 (COVID-19) pandemic. Adjuvants are …

Synthetic mRNA represents an exciting cancer vaccine technology for the implementation of
effective cancer immunotherapy. However, inefficient in vivo mRNA delivery along with a …

Nanoparticle-based delivery systems for cancer immunotherapies aim to improve the safety
and efficacy of these treatments through local delivery to specialized antigen-presenting …

Imidazoquinoline derivatives (IMDs) and related compounds function as synthetic agonists
of Toll-like receptors 7 and 8 (TLR7/8) and one is FDA approved for topical antiviral and skin …

A priority in cancer research is to innovate therapies that are not only effective against tumor
progression but also address comorbidities such as cachexia that limit quality and quantity …

Toward precision adjuvants: optimizing science and safety : Current Opinion in Pediatrics
Toward precision adjuvants: optimizing science and safety : Current Opinion in Pediatrics Log …

The generation of specific humoral and cellular immune responses plays a pivotal role in the
development of effective vaccines against tumors. Especially the presence of antigen …

606Recent clinical successes using therapeutic nucleic acids (TNAs) have accelerated the
transition of nucleic acid nanotechnology toward therapeutic applications. Significant …

The low therapeutic efficacy of current cancer immunotherapy is related to nonimmunogenic
and immunosuppressive tumor microenvironments (TMEs). To overcome these limitations …