OP-EHEA191011_online 2313..2340 Page 1 Low-density lipoproteins cause atherosclerotic
cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus …

Importance Recent clinical and imaging studies underscore that major adverse cardiac
events (MACE) outcomes are associated not solely with severe coronary obstructions …

Percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) are
considered revascularization procedures, but only CABG can prolong life in stable coronary …

Background Patients with obstructive coronary artery disease (CAD) are at high risk for
cardiovascular disease (CVD) events. However, it remains unclear whether the high risk is …

It has been believed that most acute coronary events result from the rupture of mildly stenotic
plaques, based on studies in which angiographic information was available from many …

Background: The association of atherosclerotic features with first acute coronary syndromes
(ACS) has not accounted for plaque burden. Objectives: The purpose of this study was to …

Importance Coronary computed tomographic angiography (coronary CTA) can characterize
coronary artery disease, including high-risk plaque. A noninvasive method of identifying …

Background: Myocardial infarction with nonobstructive coronary arteries (MINOCA) occurs in
5% to 10% of all patients with myocardial infarction. Clinical trials of secondary prevention …

Understanding the natural history of coronary artery atherosclerosis is necessary to
determine prognosis and prescribe effective therapies. Traditional management of coronary …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted as the document was compiled through …