Next-generation nanomaterials: advancing ocular anti-inflammatory drug therapy

J Wei, J Mu, Y Tang, D Qin, J Duan, A Wu - Journal of nanobiotechnology, 2023 - Springer
Ophthalmic inflammatory diseases, including conjunctivitis, keratitis, uveitis, scleritis, and
related conditions, pose considerable challenges to effective management and treatment …

Artificial cornea: past, current, and future directions

G Holland, A Pandit, L Sánchez-Abella, A Haiek… - Frontiers in …, 2021 - frontiersin.org
Corneal diseases are a leading cause of blindness with an estimated 10 million patients
diagnosed with bilateral corneal blindness worldwide. Corneal transplantation is highly …

The landscape of clinical trials in corneal regeneration: A systematic review of tissue engineering approaches in corneal disease

S Boroumand, M Rahmani, F Sigaroodi… - … Research Part B …, 2024 - Wiley Online Library
The limited availability of a healthy donor cornea and the incidence of allograft failure led
researchers to seek other corneal substitutes via tissue engineering. Exploring the trend of …

Advanced bioengineering strategies broaden the therapeutic landscape for corneal failure

R Al Monla, V Daien, F Michon - Frontiers in Bioengineering and …, 2024 - frontiersin.org
The cornea acts as the eye foremost protective layer and is essential for its focusing power.
Corneal blindness may arise from physical trauma or conditions like dystrophies, keratitis …

A review of the diagnosis and treatment of limbal stem cell deficiency

A Kate, S Basu - Frontiers in Medicine, 2022 - frontiersin.org
Limbal stem cell deficiency (LSCD) can cause significant corneal vascularization and
scarring and often results in serious visual morbidity. An early and accurate diagnosis can …

Keratoprosthesis in dry eye disease

S Sharma, PR Donthineni, G Iyer… - Indian Journal of …, 2023 - journals.lww.com
Bilateral corneal blindness with severe dry eye disease (DED), total limbal stem cell
deficiency with underlying corneal stromal scarring and vascularization, combined with …

[HTML][HTML] Surgical management of limbal stem cell deficiency

G Iyer, B Srinivasan, S Agarwal, M Agarwal… - Asia-Pacific Journal of …, 2020 - Elsevier
Abstract Treatment of limbal stem cell deficiency is challenging. Multiple options can be
adopted according to the underlying cause and the patient and physician preferences. Stem …

Clinical aspects of Stevens-Johnson syndrome/toxic epidermal necrolysis with severe ocular complications in India

SS Shanbhag, VS Sangwan, A Singh… - Frontiers in …, 2021 - frontiersin.org
Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a spectrum of rare,
severe immunological blistering skin reactions which are triggered by medication intake or …

Print me a cornea-Are we there yet?

MB Thomas, S Selvam, P Agrawal, P Bellur… - Bioprinting, 2022 - Elsevier
Corneal diseases are the third most prevalent cause of blindness after cataract and
glaucoma. It is estimated that about 5 million people in the world are affected by bilateral …

Long-term anatomical and functional survival of Boston type 1 keratoprosthesis in congenital aniridia

A Dyer, A De Faria, G Julio, J Álvarez de Toledo… - Frontiers in …, 2021 - frontiersin.org
Purpose: To analyze the long-term anatomical survival, functional survival, and
complications of Boston type 1 keratoprosthesis (KPro) in the eyes with congenital aniridia …