Neuronal networks are capable of undergoing rapid structural and functional changes called plasticity, which are essential for shaping circuit function during nervous system …
Y Zhang, SA Sloan, LE Clarke, C Caneda, CA Plaza… - Neuron, 2016 - cell.com
The functional and molecular similarities and distinctions between human and murine astrocytes are poorly understood. Here, we report the development of an immunopanning …
AV Molofsky, R Krenick, E Ullian, H Tsai… - Genes & …, 2012 - genesdev.cshlp.org
Astrocytes are no longer seen as a homogenous population of cells. In fact, recent studies indicate that astrocytes are morphologically and functionally diverse and play critical roles in …
W Peng, X Liu, G Ma, Z Wu, Z Wang, X Fei, M Qin… - Cell discovery, 2023 - nature.com
Astrocytes play a crucial role in regulating sleep–wake behavior, and adenosine signaling is generally thought to be involved. Here we show multiple lines of evidence supporting that …
OA Bayraktar, LC Fuentealba… - Cold Spring …, 2015 - cshperspectives.cshlp.org
Astrocytes have many roles within the brain parenchyma, and a subpopulation restricted to germinal niches functions as neural stem cells (NSCs) that produce various types of …
Astrocytes are the predominant cell type in the brain and perform key functions vital to CNS physiology, including blood brain barrier formation and maintenance, synaptogenesis …
M Blanchette, R Daneman - Mechanisms of development, 2015 - Elsevier
The central nervous system (CNS) is vascularized by a dense capillary network that is critical to deliver oxygen and nutrients, and remove carbon dioxide and waste products, from …
Astrocytes, the most abundant cells in the central nervous system, promote synapse formation and help to refine neural connectivity. Although they are allocated to spatially …
TL Stackhouse, A Mishra - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Neurovascular coupling is a crucial mechanism that matches the high energy demand of the brain with a supply of energy substrates from the blood. Signaling within the neurovascular …