Structural–functional analysis of bacteriophage T7 RNA polymerase

VL Tunitskaya, SN Kochetkov - Biochemistry (Moscow), 2002 - Springer
This review summarizes our results of the structural and functional studies of bacteriophage
T7 DNA-dependent RNA polymerase (T7 RNAP). Particular features of this enzyme (the …

[HTML][HTML] Recent studies of T7 RNA polymerase mechanism

SN Kochetkov, EE Rusakova, VL Tunitskaya - FEBS letters, 1998 - Elsevier
Bacteriophage T7 RNA polymerase (T7 RNAP) is known to be one of the simplest enzymes
catalyzing RNA synthesis. In contrast to most RNA polymerases known, this enzyme …

Origin of hepatitis delta virus mRNA

S Gudima, SY Wu, CM Chiang, G Moraleda… - Journal of …, 2000 - Am Soc Microbiol
Hepatitis delta virus (HDV) is unique relative to all known animal viruses, especially in terms
of its ability to redirect host RNA polymerase (s) to transcribe its 1,679-nucleotide (nt) circular …

Reconstitution in cultured cells of replicating HDV RNA from pairs of less than full-length RNAs

SO Gudima, J Chang, JM Taylor - RNA, 2005 - rnajournal.cshlp.org
The genome of hepatitis delta virus (HDV) is a small single-stranded circular RNA that is
replicated via RNA-directed RNA synthesis. This makes use of a host RNA polymerase …

Features affecting the ability of hepatitis delta virus RNAs to initiate RNA-directed RNA synthesis

SO Gudima, J Chang, JM Taylor - Journal of virology, 2004 - Am Soc Microbiol
In models of the replication of human hepatitis delta virus (HDV) RNA, it is generally
assumed that circular RNAs are the only templates. However, noncircular HDV RNAs are …

Immunogenic properties of reverse transcriptase of HIV type 1 assessed by DNA and protein immunization of rabbits

MG Isaguliants, SO Gudima, OV Ivanova… - AIDS research and …, 2000 - liebertpub.com
Genetic immunization may be one way to prime individuals for a subsequent broad anti-HIV-
1 immune response. Reverse transcriptase of HIV-1 (RT) presents a selective target for …

Method for rapid analysis of mutant RNA polymerase activity on templates containing unnatural nucleotides

T Egorova, E Shuvalova, S Mukba, A Shuvalov… - International Journal of …, 2021 - mdpi.com
Pairs of unnatural nucleotides are used to expand the genetic code and create artificial DNA
or RNA templates. In general, an approach is used to engineer orthogonal systems capable …

Superinfection with woodchuck hepatitis virus strain WHVNY of livers chronically infected with strain WHV7

L Rodrigues, N Freitas, BV Kallakury, S Menne… - Journal of …, 2015 - Am Soc Microbiol
The determinants of the maintenance of chronic hepadnaviral infection are yet to be fully
understood. A long-standing unresolved argument in the hepatitis B virus (HBV) research …

The role of sequence context, nucleotide pool balance and stress in 2′-deoxynucleotide misincorporation in viral, bacterial and mammalian RNA

J Wang, H Dong, YH Chionh, ME McBee… - Nucleic acids …, 2016 - academic.oup.com
Abstract The misincorporation of 2′-deoxyribonucleotides (dNs) into RNA has important
implications for the function of non-coding RNAs, the translational fidelity of coding RNAs …

The solution structure of [d(CGC)r(aaa)d(TTTGCG)]2: hybrid junctions flanked by DNA duplexes

ST Hsu, MT Chou, JW Cheng - Nucleic Acids Research, 2000 - academic.oup.com
The solution structure and hydration of the chimeric duplex [d (CGC) r (aaa) d (TTTGCG)] 2,
in which the central hybrid segment is flanked by DNA duplexes at both ends, was …